(E)-2-hepten-1-yl acetate

(E)-2-hepten-1-yl acetate is a chemical ester with the molecular formula C₉H₁₆O₂, belonging to the class of aliphatic esters commonly used for their distinctive fruity aromas. This compound exhibits an odor profile described as sweet and waxy with tropical fruit nuances comparable to kiwi and pineapple. Known by synonyms including hept-trans-2-en-1-yl acetate and acetic acid trans-2-hepten-1-yl ester, it is featured in the flavor and fragrance industry for its ability to mimic natural fruit notes. The substance is listed under FEMA number 4125 and is referenced in authoritative chemical databases such as PubChem, where it is cataloged under CID 5363203. It is typically synthesized or derived for incorporation into flavor formulations and aroma products.

(E)-2-hepten-1-yl acetate occurs naturally in passion fruit yellow aroma profiles, contributing to its characteristic fruity scent. It serves important roles in flavor and fragrance applications, particularly where berry and tropical fruit notes are desired. Regulatory evaluations including FEMA (US) recognize it under number 4125 with established guidelines for safe use. Its application extends to flavoring candies and fats, where its tropical and sweet facets enhance sensory appeal. It is utilized in formulations requiring nuanced fruit aromas, supporting its value in both food and fragrance industries.

(E)-2-hepten-1-yl acetate possesses a moderate molecular weight of approximately 156.22 g/mol, with a chemical formula C₉H₁₆O₂. It features a boiling range near 192–193 °C at standard atmospheric pressure, facilitating handling and incorporation in flavor formulations. The compound displays a specific gravity between 0.889 and 0.895 at 25 °C, indicating a density less than water. Its refractive index ranges from 1.428 to 1.434 at 20 °C. The vapor pressure is low, about 0.409 mmHg at 25 °C, aligning with typical ester volatilities. It is soluble in alcohols and exhibits limited solubility in water, estimated around 158.9 mg/L at 25 °C. The logP value of approximately 3.11 (estimated) suggests moderate lipophilicity, relevant to its behavior in fat-containing matrices and solvent systems. These properties influence its volatility, scent release, and stability in formulations.

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HMDB (The Human Metabolome Database):	HMDB32307
FooDB:	FDB009552
Export Tariff Code:	2915.39.4550
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Safety information

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for (E)-2-hepten-1-yl acetate usage levels up to:
	5.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU):		0.012 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA):		0.01 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI):		1700 (μg/person/day)
Threshold of Concern:		1800 (μg/person/day)
Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
Click here to view publication 22
		average usual ppm	average maximum ppm
baked goods:		10.00000	50.00000
beverages(nonalcoholic):		5.00000	25.00000
beverages(alcoholic):		-	-
breakfast cereal:		5.00000	25.00000
cheese:		7.00000	35.00000
chewing gum:		-	-
condiments / relishes:		5.00000	25.00000
confectionery froastings:		10.00000	50.00000
egg products:		-	-
fats / oils:		5.00000	25.00000
fish products:		2.00000	10.00000
frozen dairy:		7.00000	35.00000
fruit ices:		10.00000	50.00000
gelatins / puddings:		5.00000	25.00000
granulated sugar:		-	-
gravies:		20.00000	100.00000
hard candy:		-	-
imitation dairy:		7.00000	35.00000
instant coffee / tea:		-	-
jams / jellies:		5.00000	25.00000
meat products:		2.00000	10.00000
milk products:		7.00000	35.00000
nut products:		-	-
other grains:		5.00000	25.00000
poultry:		2.00000	10.00000
processed fruits:		7.00000	35.00000
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		5.00000	25.00000
snack foods:		10.00000	50.00000
soft candy:		-	-
soups:		5.00000	25.00000
sugar substitutes:		-	-
sweet sauces:		5.00000	25.00000
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
		average usage mg/kg	maximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0):		5.70000	12.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0):		1.50000	14.25000
Edible ices, including sherbet and sorbet (03.0):		-	-
Processed fruit (04.1):		-	-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2):		5.00000	5.03000
Confectionery (05.0):		5.50000	14.46000
Chewing gum (05.3):		6.02000	20.87000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0):		4.80000	11.55000
Bakery wares (07.0):		5.00000	17.00000
Meat and meat products, including poultry and game (08.0):		0.90000	2.98000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0):		-	-
Eggs and egg products (10.0):		-	-
Sweeteners, including honey (11.0):		-	-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0):		2.00000	5.00000
Foodstuffs intended for particular nutritional uses (13.0):		-	-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1):		2.00000	4.43000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2):		1.00000	2.00000
Ready-to-eat savouries (15.0):		2.50000	4.50000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0):		-	-

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 a,ß-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19 View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 71 Revision 1 (FGE.71Rev1): consideration of aliphatic, linear, a,ß-unsaturated alcohols, aldehydes, carboxylic acids, and related esters evaluated by JECFA (63rd and 69th meeting) structurally related to flavouring substances evaluated in FGE.05Rev3 View page or View pdf

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EPA Substance Registry Services (TSCA):16939-73-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :5363203

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

[(E)-hept-2-enyl] acetate

Chemidplus:0016939734