We have found
46590
results matching your criteria.
Please wait while we search...
hexyl cinnamate
Hexyl cinnamate is an ester compound recognized for its balsamic, woody scent, used primarily in fragrance applications as a cypress oil substitute.
General Material Description
Hexyl cinnamate is an ester compound chemically described as hexyl (2E)-3-phenyl-2-butenoate with the molecular formula C15H20O2. It appears as a colorless to pale yellow liquid and is primarily valued for its balsamic odor characterized by woody and powdery notes. Common synonyms include hexyl (E)-3-phenylprop-2-enoate and cinnamic acid hexyl ester. This compound belongs to the class of cinnamic acid esters and is linked to the PubChem compound database under CID 6437300. Hexyl cinnamate is typically synthesized via esterification of cinnamic acid with hexanol and is sourced for its use in fragrance formulations, especially as a component imparting balsamic and woody aromas.
Occurrence, Applicability & Potential Uses
Hexyl cinnamate occurs naturally in certain plant extracts and is extensively utilized in the fragrance industry for its balsamic, woody aromatic qualities. Its scent profile includes resembling cypress oil, making it a preferred replacement in formulations requiring similar olfactory characteristics. This fragrance agent is incorporated into products requiring powdery and sap-like nuances and contributes dry woody notes. The compound’s use is regulated under IFRA (Global), which recommends usage limits of up to 3.0% in fragrance concentrates. It is not approved for flavoring purposes, aligning with safety assessments across various regulatory frameworks including REACH (EU).
Physico-Chemical Properties Summary
Hexyl cinnamate exhibits a specific gravity of approximately 0.997 at 25 °C, indicative of a near neutral density compared to water. Its vapor pressure is extremely low at 0.000126 mmHg at 25 °C, suggesting low volatility at ambient temperatures. The estimated log P value of 4.833 reflects a high lipophilicity, consistent with its limited water solubility and good solubility in alcohol solvents, facilitating incorporation in oil-based fragrance systems. The flash point, measured at 354 °F (179 °C), indicates considerable thermal stability and helps inform safe handling practices. These physicochemical parameters assist formulators in predicting the material’s behavior in various fragrance matrices and ensure compatibility and stability in end products.
FAQ
What is hexyl cinnamate and what are its main characteristics?
Hexyl cinnamate is an ester compound derived from cinnamic acid and hexanol, known chemically as hexyl (2E)-3-phenyl-2-butenoate. It possesses a balsamic, woody odor with powder and sap-like nuances. This colorless to pale yellow liquid is primarily used as a fragrance ingredient, valued for its ability to impart cypress-like and dry woody scents in perfumery and related applications.
How is hexyl cinnamate used and where does it typically occur?
Hexyl cinnamate appears naturally in certain botanical extracts but is most commonly industrially synthesized for use in fragrance products. Its aroma profile makes it suitable as a replacement for natural cypress oil in formulations. It is used to add balsamic, woody, powdery, and sap-like notes in perfumes, cosmetics, and personal care items. It dissolves well in alcoholic solvents and is favored for oil-based fragrance systems.
What regulations and safety considerations apply to hexyl cinnamate?
Hexyl cinnamate is regulated by IFRA (International Fragrance Association, Global), which recommends usage limits up to 3.0% in fragrance concentrates to ensure safe use. It is not authorized for use as a flavoring agent. Under the European REACH regulation, it is registered and monitored for industrial and commercial safety. No specific hazard classifications have been identified under OSHA standards. Safety data indicates no notable oral, dermal, or inhalation toxicity has been conclusively determined.
US / EU / FDA / JECFA / FEMA / Scholar / Patents
| Google Scholar | Start search |
| Google Books | Start search |
| Google Patents | Start search |
| Perfumer & Flavorists | Start search |
| EU Patents | Start search |
| PubMeb | Start search |
| NCBI | Start search |
Other Information
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
General Material Information
| Preferred name | hexyl cinnamate |
| Trivial Name | Hexyl cinnamate |
| Short Description | hexyl (2E)-3-phenyl-2-butenoate |
| Formula | C15 H20 O2 |
| CAS Number | 3488-00-4 |
| ECHA Number | 222-479-7 |
| FDA UNII | 532UJ0Y6RI |
| Nikkaji Number | J216.149D |
| NMR Predictor | External link |
| Synonyms |
|
PhysChem Properties
| Material listed in food chemical codex | No |
| Molecular weight | 232.32279968262 |
| Specific gravity | @ 25 °C |
| Pounds per Gallon | |
| Vapor Pressure | 0.000126 mmHg @ 25 °C |
| Flash Point TCC Value | 178.89 °C TCC |
| logP (o/w) | 4.833 est |
| Solubility | |
| alcohol | Yes |
| water, 2.296 mg/L @ 25 °C (est) | Yes |
| water | No |
Organoleptic Properties
| Odor Type: Balsamic | |
| cypress, cumin, fruity, balsamic | |
| Luebke, William tgsc, (1993) | At 100.00 %. cypress cuminic acetate fruity balsam |
Potential Uses
| Applications | |
| Odor purposes | Balsam , Cypress oil replacer , Powder , Sap , Woody |
| Other purposes | Dry |
Safety Information
Safety information
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in use information
| Category: | |||
| fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for hexyl cinnamate usage levels up to: | |||
| 3.0000 % in the fragrance concentrate. | |||
| Recommendation for hexyl cinnamate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety references
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :6437300 |
| National Institute of Allergy and Infectious Diseases:Data |
| hexyl (E)-3-phenylprop-2-enoate |
| Chemidplus:0003488004 |