We have found 46587 results matching your criteria.
Please wait while we search...
  1. 1.
    General Material Information
  2. 2.
    PhysChem Properties
  3. 3.
    Occurrences
  4. 4.
    Organoleptic Properties
  5. 5.
    Suppliers
  6. 6.
    Potential Uses
  7. 7.
    Regulatory & Documentation
  8. 8.
    Safety Information
  9. 9.
    Other Information
  10. 10.
    Blenders & Components
  11. 11.
    Literature & References

menthone lactone

Chemical Structure

General Material Information

Preferred name menthone lactone
Trivial Name 3,7-Dimethyl-6-octanolide
Short Description 6-hydroxy-3,7-dimethyloctanoic acid lactone
Formula C10 H18 O2
CAS Number 499-54-7
FEMA Number 3355
Flavis Number 10.027
ECHA Number 207-882-8
FDA UNII 30YQY8O31P
Nikkaji Number J182.248I
Beilstein Number 81481
COE Number 11833
xLogP3-AA 2.70 (est)
NMR Predictor External link
JECFA Food Flavoring 237 6-hydroxy-3,7-dimethyloctanoic acid lactone
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 499-54-7 ; 6-HYDROXY-3,7-DIMETHYLOCTANOIC ACID LACTONE
Synonyms
  • 3,7-dimethyl octano-1,6-lactone
  • 3,7-dimethyl-6-octanolide
  • 3,7-dimethyloctano-1,6-lactone
  • 6-hydroxy-3,7-dimethyl caprylic acid epsilon-lactone
  • 6-hydroxy-3,7-dimethyl octanoic acid lactone
  • 6-hydroxy-3,7-dimethyloctanoic acid lactone
  • 3-methyl-6-isopropyl-6-hexanolide
  • 4-methyl-7-(1-methyl ethyl)-2-oxepanone
  • 4-methyl-7-(1-methylethyl)-2-oxepanone
  • 4-methyl-7-(1-methylethyl)oxepan-2-one
  • 4-methyl-7-(propan-2-yl)oxepan-2-one
  • 4-methyl-7-isopropyl-2-oxepanone
  • 4-methyl-7-propan-2-yloxepan-2-one
  • 2-oxepanone, 4-methyl-7-(1-methylethyl)-
  • iso propyl methyl oxepanone
  • 7-iso propyl-4-methyl oxepan-2-one
  • 7-iso propyl-4-methyloxepan-2-one
  • 4-methyl-7-propan-2-yloxepan-2-one
  • 2-Oxepanone, 4-methyl-7-(1-methylethyl)-
  • 4-Methyl-7-(1-methylethyl)-2-oxepanone
  • 3,7-Dimethyl-6-octanolide
  • 7-(1-Methylethyl)-4-methyl-2-oxepanone
  • 4-Methyl-7-isopropyl-ε-caprolactone
  • 4-Methyl-7-isopropyloxepan-2-one
  • 7-Isopropyl-4-methyloxepan-2-one

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar Start search
Google Books Start search
Google Patents Start search
Perfumer & Flavorists Start search
EU Patents Start search
PubMeb Start search
NCBI Start search

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
KEGG (GenomeNet):C18066
HMDB (The Human Metabolome Database):HMDB40330
FooDB:FDB020055
Export Tariff Code:2932.29.6000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 170.25186157227
Specific gravity @ 25 °C
Pounds per Gallon 8.038 to 8.096
Refractive Index 1.457 to 1.461 @ 20 °C
Boiling Point 247 to 248°C @ 760 mm Hg
Vapor Pressure 0.024 mmHg @ 25 °C
Flash Point TCC Value 96.11 °C TCC
logP (o/w) 2.357 est
Solubility
alcohol Yes
water Yes
water, 525.8 mg/L @ 25 °C (est) Yes

Organoleptic Properties

Odor Type: Caramellic
caramellic, maple, sugar brown sugar, molasses
General comment At 1.00 % in propylene glycol. maple syrup brown sugar

Occurrences

Potential Uses

Applications
Odor purposes Pennyroyal, Peppermint
Flavoring purposes Pennyroyal
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
gavage-rat LD50 [sex: M,F] > 5000 mg/kg
(Lewis & Palanker, 1979a)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for menthone lactone usage levels up to:
1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 6
Click here to view publication 6
average usual ppmaverage maximum ppm
baked goods: -500.00000
beverages(nonalcoholic): -300.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -200.00000
fruit ices: -200.00000
gelatins / puddings: -500.00000
granulated sugar: --
gravies: --
hard candy: -200.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):499-54-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :62349
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
4-methyl-7-propan-2-yloxepan-2-one
Chemidplus:0000499547