Preferred name | dextro-camphor |
Trivial Name | (+)-Camphor |
Short Description | D-camphor |
Formula | C10 H16 O |
CAS Number | 464-49-3 |
Deleted CAS Number | 68546-28-1 |
FEMA Number | 2230 |
Flavis Number | 7.215 |
ECHA Number | 207-355-2 |
FDA UNII | N20HL7Q941 |
Nikkaji Number | J43.294F |
Beilstein Number | 2042745 |
MDL | MFCD00064149 |
COE Number | 140 |
xLogP3-AA | 2.20 (est) |
Bio Activity Summary | External link |
NMR Predictor | External link |
JECFA Food Flavoring | 1395 D-camphor |
FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm | 464-49-3 ; D-CAMPHOR |
Synonyms |
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Google Scholar | Start search |
Google Books | Start search |
Google Patents | Start search |
Perfumer & Flavorists | Start search |
EU Patents | Start search |
PubMeb | Start search |
NCBI | Start search |
Leffingwell: | Chirality or Article |
(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one | |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 464-49-3 |
Pubchem (cid): | 159055 |
Pubchem (sid): | 134973831 |
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
FDA Indirect Additives used in Food Contact Substances: | View |
CHEBI: | View |
CHEMBL: | View |
UM BBD: | Search |
KEGG (GenomeNet): | C00808 |
HMDB (The Human Metabolome Database): | Search |
FooDB: | FDB009067 |
Export Tariff Code: | 2914.21.1000 |
Typical G.C. | |
VCF-Online: | VCF Volatile Compounds in Food |
ChemSpider: | View |
Wikipedia: | View |
Material listed in food chemical codex | No |
Molecular weight | 152.23672485352 |
Vapor Pressure | 4 mmHg @ 25 °C |
Vapor Density | 5.24 |
Flash Point TCC Value | 64.44 °C TCC |
logP (o/w) | 3.04 |
Solubility | |
alcohol | Yes |
water, 100 mg/L @ 25 °C (exp) | Yes |
water | No |
glycerin | No |
Odor Type: Camphoreous | |
camphoreous, minty, phenolic, herbal, woody, medicinal, mentholic, cooling, green | |
Odor strength | high , recommend smelling in a 10.00 % solution or less |
Substantivity | 160 hour(s) at 20.00 % in dipropylene glycol |
Luebke, William tgsc, (1988) | At 10.00 % in dipropylene glycol. camphor minty phenolic herbal woody |
Mosciano, Gerard P&F 18, No. 2, 38, (1993) | Camphoreous, medicinal, mentholic, with a cooling green nuance |
Flavor Type: Medicinal | |
medicinal, camphoreous, mentholic, woody | |
Mosciano, Gerard P&F 18, No. 2, 38, (1993) | At 20.00 ppm. Medicinal, camphoreous, mentholic and woody |
(data available) |
Applications | |
Odor purposes | Basil oil replacer, Camphor tree bark, Cologne, Floral, Lavandin, Lavender, Lavender spike lavender, Nutmeg, Orange blossom, Pennyroyal, Pine, Rosemary, Sage, Sassafras, Woody |
Flavoring purposes | Camphor tree bark, Lavender spike lavender, Pennyroyal |
Other purposes | Disinfectants |
Cosmetic purposes | Perfuming agents |
Preferred SDS: View | |
European information : | |
Most important hazard(s): | |
Xn - Harmful. | |
R 10 - Flammable. R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
Hazards identification | |
Classification of the substance or mixture | |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
None found. | |
GHS Label elements, including precautionary statements | |
Pictogram | |
Hazard statement(s) | |
None found. | |
Precautionary statement(s) | |
None found. | |
Oral/Parenteral Toxicity: | |
oral-mouse LD50 1310 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. intraperitoneal-cat LDLo 400 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. intravenous-mouse LD90 525 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. intraperitoneal-rat LDLo 3500 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. | |
Dermal Toxicity: | |
subcutaneous-mouse LDLo 2200 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. subcutaneous-rat LDLo 1700 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978. | |
Inhalation Toxicity: | |
Not determined |
Category: | |||
flavor and fragrance agents | |||
RIFM Fragrance Material Safety Assessment: Search | |||
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
Recommendation for dextro-camphor usage levels up to: | |||
3.0000 % in the fragrance concentrate. | |||
Maximised Survey-derived Daily Intakes (MSDI-EU): | 50.00 (μg/capita/day) | ||
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
publication number: 3 | |||
Click here to view publication 3 | |||
average usual ppm | average maximum ppm | ||
baked goods: | - | 11.00000 | |
beverages(nonalcoholic): | - | - | |
beverages(alcoholic): | - | - | |
breakfast cereal: | - | - | |
cheese: | - | - | |
chewing gum: | - | - | |
condiments / relishes: | - | 20.00000 | |
confectionery froastings: | - | - | |
egg products: | - | - | |
fats / oils: | - | - | |
fish products: | - | - | |
frozen dairy: | - | 0.10000 | |
fruit ices: | - | 0.10000 | |
gelatins / puddings: | - | - | |
granulated sugar: | - | - | |
gravies: | - | - | |
hard candy: | 1.10000 | 25.00000 | |
imitation dairy: | - | - | |
instant coffee / tea: | - | - | |
jams / jellies: | - | - | |
meat products: | - | - | |
milk products: | - | - | |
nut products: | - | - | |
other grains: | - | - | |
poultry: | - | - | |
processed fruits: | - | - | |
processed vegetables: | - | - | |
reconstituted vegetables: | - | - | |
seasonings / flavors: | - | - | |
snack foods: | - | - | |
soft candy: | - | - | |
soups: | - | - | |
sugar substitutes: | - | - | |
sweet sauces: | - | - |
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Camphor in flavourings and other food ingredients with flavouring properties - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission View page or View pdf |
Safety and efficacy of secondary alicyclic saturated and unsaturated alcohols, ketones, ketals and esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols from chemical group 8 when used as flavourings for all animal species View page or View pdf |
EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):464-49-3 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :159055 |
National Institute of Allergy and Infectious Diseases:Data |
WISER:UN 2717 |
WGK Germany:1 |
(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one |
Chemidplus:0000464493 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:EX1260000 for cas# 464-49-3 |