(R)-massoia lactone

General Material Information

Preferred name	(R)-massoia lactone
Trivial Name	Massoia lactone
Short Description	(R)-5-hydroxy-2-decenoic acid lactone
Formula	C10 H16 O2
CAS Number	51154-96-2
Deleted CAS Number	38733-05-0
FEMA Number	3744
FDA UNII	847O2V0IOA
Nikkaji Number	J11.190B
Beilstein Number	4177048
xLogP3-AA	3.10 (est)
NMR Predictor	External link
JECFA Food Flavoring	246 (R)-5-hydroxy-2-decenoic acid delta-lactone
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	51154-96-2 ; 5-HYDROXY-2-DECENOIC ACID DELTA-LACTONE
Synonyms	(R)- cocolactone (R)-5,6-dihydro-6-pentyl-2H-pyran-2-one (R)-5-hydroxy-2-decenoic acid lactone (R)- massoia lactone nat (R)- massoia lactone natural (R)- massoialactone (R)-()- massoialactone (R)- massoilactone (6R)-6-pentyl-5,6-dihydro-2H-pyran-2-one 2H- pyran-2-one, 5,6-dihydro-6-pentyl-, (6R)- 2H- pyran-2-one, 5,6-dihydro-6-pentyl-, (R)- (6R)-6-pentyl-5,6-dihydropyran-2-one 2H-Pyran-2-one, 5,6-dihydro-6-pentyl-, (6R)- 2H-Pyran-2-one, 5,6-dihydro-6-pentyl-, (R)- (6R)-5,6-Dihydro-6-pentyl-2H-pyran-2-one Massoia lactone (R)-(-)-Massoialactone Massoilactone (-)-Massoialactone (-)-(6R)-Massoialactone (6R)-(-)-Massoialactone (-)-Massoja decalactone (-)-Massoilactone Massoya lactone (R)-6-Pentyl-5,6-dihydro-2H-pyran-2-one

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB34452
FooDB:	FDB012861
Export Tariff Code:	2932.29.6000
Typical G.C.
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Material listed in food chemical codex	No
Molecular weight	168.2359161377
Specific gravity	@ 25 °C
Pounds per Gallon	8.171 to 8.254
Refractive Index	1.467 to 1.477 @ 20 °C
Boiling Point	170 to 174°C @ 760 mm Hg
Vapor Pressure	0.003 mmHg @ 25 °C
Flash Point TCC Value	93.33 °C TCC
logP (o/w)	2.54 est
Solubility
alcohol	Yes
water, 614.3 mg/L @ 25 °C (est)	Yes

Odor Type: Coconut
sweet, coconut, lactonic, creamy, milky, waxy
General comment	At 1.00 % in propylene glycol. sweet coconut meat lactonic creamy milky waxy
Mosciano, Gerard P&F 19, No. 1, 27, (1994)	Sweet, coconut meat, lactonic, creamy, milky and waxy
Flavor Type: Coconut
creamy, coconut, milky, green, fruity
Mosciano, Gerard P&F 19, No. 1, 27, (1994)	At 20.00 ppm. Creamy, coconut, milky, green and slightly fruity
MASSOIA LACTONE is a cost effective natural lactone which brings a very particular creamy, coconut and spicy profile to all kinds of dairy, fruit and nut flavors.	Very pleasant creamy, coconut, spicy and celery notes

European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 43 - May cause sensitisation by skin contact. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 1890 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 40, 1964.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavoring agents
IFRA Critical Effect:
Dermal sensitization
	View the IFRA Standard
Recommendation for (R)-massoia lactone usage levels up to:
	PROHIBITED: Should not be used as a fragrance ingredient.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 14
Click here to view publication 14
		average usual ppm	average maximum ppm
baked goods:		-	1.00000
beverages(nonalcoholic):		-	0.50000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	4.00000
condiments / relishes:		-	-
confectionery froastings:		-	1.00000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	0.20000
hard candy:		-	4.00000
imitation dairy:		-	2.00000
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	0.20000
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	0.50000
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

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EPA Substance Registry Services (TSCA):51154-96-2

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :642793

National Institute of Allergy and Infectious Diseases:Data

(6R)-6-pentyl-5,6-dihydropyran-2-one

Chemidplus:0051154962