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General Material Information

Preferred name (Z)-6-nonenal
Trivial Name cis-6-Nonenal
Short Description cis-6-nonenal
Formula C9 H16 O
CAS Number 2277-19-2
FEMA Number 3580
Flavis Number 5.059
ECHA Number 218-900-9
FDA UNII D8027Y6086
Nikkaji Number J59.357E
Beilstein Number 2323664
MDL MFCD00014683
COE Number 661
xLogP3-AA 2.30 (est)
NMR Predictor External link
JECFA Food Flavoring 325 cis-6-nonenal
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 2277-19-2 ; CIS-6-NONENAL
Synonyms
  • (Z)- non-6-en-1-al
  • (6Z)- non-6-enal
  • (Z)- non-6-enal
  • cis-6-non-6-enal
  • non-6(cis)-enal
  • non-6(Z)-enal
  • (Z)-6-nonen-1-al
  • cis-6-nonen-1-al
  • cis-6-nonen-1-al, no antioxidant
  • (6Z)-6-nonenal
  • (Z)-6-nonenal
  • C6 nonenal
  • cis 6-nonenal
  • cis-6-nonenal
  • 6-nonenal, (6Z)-
  • 6-nonenal, (Z)-
  • 6-nonenal, cis-
  • (Z)-non-6-enal
  • 6-Nonenal, (6Z)-
  • 6-Nonenal, (Z)-
  • (6Z)-6-Nonenal
  • 6-Nonenal, cis-
  • cis-6-Nonenal

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB30958
FooDB:FDB002937
Export Tariff Code:2912.19.9000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 140.2257232666
Specific gravity @ 25 °C
Pounds per Gallon 7.006 to 7.089
Refractive Index 1.436 to 1.446 @ 20 °C
Acid Value 5 max KOH/g
Vapor Pressure 0.449 mmHg @ 25 °C
Flash Point TCC Value 65.56 °C TCC
logP (o/w) 3.113 est
Shelf life 12 months (or longer if stored properly.)
Storage notes Store under nitrogen.
Solubility
alcohol Yes
water, 204.9 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Melon
green, cucumber, melon, cantaloupe, honeydew, waxy, vegetable, orris, violet leaf, woody
Odor strength very high , recommend smelling in a 1.00 % solution or less
Substantivity > 252 hour(s) at 100.00 %
Luebke, William tgsc, (2003) At 1.00 % in dipropylene glycol. green cucumber melon cantaloupe honeydew waxy vegetable orris violet leaf
Mosciano, Gerard P&F 20, No. 1, 31, (1995) Green cucumber and melon with a woody orris-type nuance
Flavor Type: Green
green, cucumber, melon, waxy, oily, watermelon, vegetable, violet leaf
General comment Green cucumber melon waxy oily watermelon vegetable violet leaf
Mosciano, Gerard P&F 20, No. 1, 31, (1995) At 25.00 ppm. Green cucumber and melon with a waxy vegetative nuance
Useful in melon flavors, especially cantaloupe, watermelon, cucumber, and tropical fruits. Can add fresh cut, crisp apple notes. Fresh, green, watermelon, melon and hints of vegetables

Occurrences

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin irritation (Category 2), H315
Eye irritation (Category 2A), H319
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
GHS Label elements, including precautionary statements
Pictogramexclamation-mark.jpg
Signal word Warning
Hazard statement(s)
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P271 - Use only outdoors or in a well-ventilated area.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 - Call a POISON CENTER or doctor/physician if you feel unwell.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P337 + P313 - IF eye irritation persists: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 5000 mg/kg
(Moreno, 1978b)

oral-mouse LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 777, 1982.

Dermal Toxicity:
skin-guinea pig LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 777, 1982.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for (Z)-6-nonenal usage levels up to:
1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 1.70 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 11
Click here to view publication 11
average usual ppmaverage maximum ppm
baked goods: -1.00000
beverages(nonalcoholic): -0.20000
beverages(alcoholic): -0.10000
breakfast cereal: -0.10000
cheese: --
chewing gum: -1.00000
condiments / relishes: -0.10000
confectionery froastings: -1.50000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.30000
fruit ices: -0.30000
gelatins / puddings: -0.50000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 6 (FGE.06): Straight-and branched-chain aliphatic unsatured primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4
View page or View pdf

Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to Flavouring Group Evaluation 5: Esters of 23 branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and 24 branched- and straight-chain unsaturated carboxylic acids from chemical groups 1, 2, and 5
View page or View pdf

Flavouring Group Evaluation 6, Revision 1 (FGE.06Rev1) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 5, Revision 1 (FGE.05Rev1):Esters of branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and branched- and straight-chain unsaturated carboxylic acids from chemical groups 1, 2, and 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) [1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 5, Revision 2 (FGE.05Rev2): Branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols from chemical groups 1, 2, 3 and 5
View page or View pdf

Safety and efficacy of non-conjugated and accumulated unsaturated straight-chain and branched-chain, aliphatic primary alcohols, aldehydes, acids, acetals and esters belonging to chemical group 4 when used as flavourings for all animal species
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):2277-19-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5362720
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(Z)-non-6-enal
Chemidplus:0002277192
RTECS:RA8509200 for cas# 2277-19-2