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methyl myristate

Chemical Structure

General Material Information

Preferred name methyl myristate
Trivial Name Methyl myristate
Short Description methyl tetradecanoate
Formula C15 H30 O2
CAS Number 124-10-7
FEMA Number 2722
Flavis Number 9.106
ECHA Number 204-680-1
FDA UNII RG9851783C
Nikkaji Number J382D
Beilstein Number 1773739
MDL MFCD00008983
COE Number 387
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 183 methyl myristate
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 124-10-7 ; METHYL MYRISTATE
Synonyms
  • methyl myristate redistilled
  • methyl N-tetradecanoate
  • methyl tetradecanoate
  • methyl-myristate (methyltetradecanoate)
  • myristic acid methyl ester
  • myristic acid methylester
  • myristic acid, methyl ester
  • tetradecanoate acid, methyl ester
  • tetradecanoic acid methyl ester
  • tetradecanoic acid, methyl ester
  • uniphat A50
  • Metholeneat 2495
  • Pastell M 14
  • NSC 5029
  • Emery 2214

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

methyl tetradecanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:124-10-7
Pubchem (cid):31284
Pubchem (sid):134974903
Flavornet:124-10-7
Pherobase:View
Publications by PubMed
Non-invasive characterization of the adipogenic differentiation of human bone marrow-derived mesenchymal stromal cells by HS-SPME/GC-MS.
Melanogenesis of methyl myristate loaded niosomes in B16F10 melanoma cells.
Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450BM3 (CYP102A1).
Polyamine-functional sterically stabilized latexes for covalently cross-linkable colloidosomes.
Biosynthesis of monomers for plastics from renewable oils.
Evaluation of an oviposition-stimulating kairomone for the yellow fever mosquito, Aedes aegypti, in Recife, Brazil.
Antioxidant and NF-κB inhibitory constituents isolated from Morchella esculenta.
Olfactory perception of oviposition-deterring fatty acids and their methyl esters by the Asian corn borer, Ostrinia furnacalis.
Chlamydomonas as a "new" organism for biodiesel production.
Overexpression of the apple alcohol acyltransferase gene alters the profile of volatile blends in transgenic tobacco leaves.
Packing density of glycolipid biosurfactant monolayers give a significant effect on their binding affinity toward immunoglobulin G.
Hydroxyapatite nanoparticles as stimulus-responsive particulate emulsifiers and building block for porous materials.
Antileukemic effects of Didemnum psammatodes (Tunicata: Ascidiacea) constituents.
Effects of pH and salt concentration on oil-in-water emulsions stabilized solely by nanocomposite microgel particles.
Toxicity studies of tetradecanoic acid, 2-sulfo-, 1-methylester, sodium salt (C14-MES).
Effect of varying the oil phase on the behavior of pH-responsive latex-based emulsifiers: demulsification versus transitional phase inversion.
Supercritical CO2 as a reaction medium for synthesis of capsaicin analogues by lipase-catalyzed transacylation of capsaicin.
[Studies on the chemical constituents from marine brown alga Ishige okamurai (3)].
Fatty acid-specific, regiospecific, and stereospecific hydroxylation by cytochrome P450 (CYP152B1) from Sphingomonas paucimobilis: substrate structure required for alpha-hydroxylation.
Antinociceptive and uterine relaxant activities of Viburnum toronis alive (Caprifoliaceae).
A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating preadipocytes.
Reaction of alpha-tocopherol in heated bulk phase in the presence of methyl linoleate (13S)-hydroperoxide or methyl linoleate.
Platelet lysis and functional perturbation by 13-methyl myristate. The major fatty acid in Flavobacterium ranacida.
Egg dispersion in codling moth: Influence of egg extract and of its fatty acid constituents.
Growth temperature-dependent variation of cell envelope lipids and antibiotic susceptibility in Stenotrophomonas (Xanthomonas) maltophilia.
Phycochemical studies on Scinaia fascicularis (Bonnemaisoniales, Rhodophyta).
Chemical characterization and biologic properties of lipopolysaccharide from Bacteroides gingivalis strains W50, W83, and ATCC 33277.
Acylation of keratinocyte transglutaminase by palmitic and myristic acids in the membrane Anchorage region.
Fatty acid profiles of Chlamydia using capillary gas chromatography.
Acetylcholine receptor-associated 43K protein contains covalently bound myristate.
Identification of ant repellent allomone produced by social waspPolistes fuscatus (Hymenoptera: Vespidae).
Autoxidation of Acholeplasma laidlawii membranes.
Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids.
Synthesis of carbon-13-labeled tetradecanoic acids.
Cellular fatty acids of Capnocytophaga species.
Cellular fatty acids of Flavobacterium meningosepticum and Flavobacterium species group IIb.
Relative autoxidative and photolytic stabilities of tocols and tocotrienols.
Cellular fatty acids of Alcaligenes and Pseudomonas species isolated from clinical specimens.
Synthesis of saturated long chain fatty acids from sodium acetate-1-C14 by Mycoplasma.
Lipid metabolism of rumen ciliates and bacteria. I. Uptake of fatty acids by Isotricha prostoma and Entodinium simplex.

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
Golm Metabolome Database:Search
HMDB (The Human Metabolome Database):HMDB30469
FooDB:FDB002338
Export Tariff Code:2915.90.1050
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 242.40249633789
Specific gravity @ 20 °C
Pounds per Gallon 7.223 to 7.248
Refractive Index 1.436 to 1.438 @ 20 °C
Melting Point 18 to 19°C @ 760 mm Hg
Acid Value 1 max KOH/g
Vapor Pressure 0.000269 mmHg @ 25 °C
Flash Point TCC Value 110 °C TCC
logP (o/w) 6.41
Solubility
alcohol Yes
dipropylene glycol Yes
fixed oils Yes
water, 0.08744 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Waxy
fatty, waxy, petal
General comment At 100.00 %. fatty waxy petal

Occurrences

Potential Uses

Applications
Odor purposes Floral, Root, Violet
Other purposes Emollients, Skin conditioning
Cosmetic purposes Skin conditioning, Skin conditioning - emollient

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for methyl myristate usage levels up to:
3.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 62.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: 0.300002.00000
beverages(nonalcoholic): 0.250000.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.250000.50000
fruit ices: 0.250000.50000
gelatins / puddings: -0.24000
granulated sugar: --
gravies: --
hard candy: -2.40000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 2, Revision 1 (FGE.02) : Branched- and straight-chain aliphatic saturated primary alcohols and related esters of primary alcohols and straight-chain carboxylic acids and one straight-chain aldehyde from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):124-10-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :31284
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
methyl tetradecanoate
Chemidplus:0000124107