laevo-(+)-tartaric acid

General Material Information

Preferred name	laevo-(+)-tartaric acid
Trivial Name	(+)-Tartaric acid
Short Description	tartaric acid (+)-, (-)-, (+/-)-, meso-
Formula	C4 H6 O6
CAS Number	87-69-4
Deleted CAS Number	1336-18-1
FEMA Number	3044
ECHA Number	201-766-0
FDA UNII	W4888I119H
Nikkaji Number	J31.839F
Beilstein Number	1725147
MDL	MFCD00064207
COE Number	18
xLogP3-AA	-1.90 (est)
Bio Activity Summary	External link
NMR Predictor	External link
JECFA Food Flavoring	621 tartaric acid (+)-, (-)-, (+/-)-, meso-
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	87-69-4 ; TARTARIC ACID, L
Synonyms	acidum tartaricum butanedioic acid, 2,3-dihydroxy-, (2R,3R)- (2R,3R)-2,3-dihydroxybutane dioic acid (R-(R,R))-2,3-dihydroxybutane dioic acid (2R,3R)-2,3-dihydroxybutanedioic acid [R-(R,R)]-2,3-dihydroxybutanedioic acid L-2,3-dihydroxybutanedioic acid 1,2-dihydroxyethane-1,2-dicarboxylic acid (2R,3R)-2,3-dihydroxysuccinic acid 2,3-dihydroxysuccinic acid delta-alpha,beta- dihydroxysuccinic acid (+)- tartaric acid (+)-(2R,3R)- tartaric acid (+)-(R,R)- tartaric acid (+)-L- tartaric acid (+)-laevo- tartaric acid (2R,3R)-(+)- tartaric acid (R,R)- tartaric acid delta- tartaric acid L- tartaric acid L-(+) - tartaric acid L-(+)- tartaric acid laevo- tartaric acid tartaric acid (+)-, (-)-, (+/-)-, meso- L- tartaric acid natural tartaric acid NF FCC granular L- threaric acid (2R,3R)-2,3-dihydroxybutanedioic acid Butanedioic acid, 2,3-dihydroxy- (2R,3R)- Tartaric acid, L-(+)- Butanedioic acid, 2,3-dihydroxy- [R-(R,R)]- Dextrotartaric acid d-α,β-Dihydroxysuccinic acid Natural tartaric acid L-Tartaric acid Tartaric acid L-(+)-Tartaric acid Threaric acid (+)-Tartaric acid 1,2-Dihydroxyethane-1,2-dicarboxylic acid (R,R)-(+)-Tartaric acid d-Tartaric acid (R,R)-Tartaric acid 2,3-Dihydroxybutanedioic acid (+)-(R,R)-Tartaric acid (2R,3R)-(+)-Tartaric acid (+)-L-Tartaric acid (2R,3R)-Tartaric acid E 334 Dihydroxysuccinic acid NSC 62778 (2R,3R)-2,3-Dihydroxysuccinic acid (+)-(2R,3R)-Tartaric acid 2,3-Dihydroxysuccinic acid

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar	Start search
Google Books	Start search
Google Patents	Start search
Perfumer & Flavorists	Start search
EU Patents	Start search
PubMeb	Start search
NCBI	Start search

Literature & References

	(2R,3R)-2,3-dihydroxybutanedioic acid
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	87-69-4
Pubchem (cid):	444305
Pubchem (sid):	134971855

Publications by PubMed
Crystal structure of 2-amino-4-methyl-pyridin-1-ium (2R,3R)-3-carb-oxy-2,3-di-hydroxy-propano-ate monohydrate.
Revisiting the sparteine surrogate: development of a resolution route to the (-)-sparteine surrogate.
The journey of l-tartaric acid in the world of enantiomerically pure bis- and trisadducts of C60 with the inherently chiral trans-3 and all-trans-3 addition patterns.
Cloning, homology modeling, and reaction mechanism analysis of a novel cis-epoxysuccinate hydrolase from Klebsiella sp.
Purification and characterization of a novel cis-epoxysuccinate hydrolase from Klebsiella sp. that produces L(+)-tartaric acid.
[Production of L(+)-tartaric acid by immobilized Rhizobium strain BK-20].
Li(+)-induced selective gelation of discrete homochiral structural isomers derived from L-tartaric acid.
[Effects of carbon and nitrogen sources on 5-keto-gluconic acid production].
Comparison of extraction protocols to determine differences in wine-extractable tannin and anthocyanin in Vitis vinifera L. cv. Shiraz and Cabernet Sauvignon grapes.
A C2-symmetric chiral pool-based flexible strategy: synthesis of (+)- and (-)-shikimic acids, (+)- and (-)-4-epi-shikimic acids, and (+)- and (-)-pinitol.
Improvement of the production efficiency of L-(+)-tartaric acid by heterogeneous whole-cell bioconversion.
Growth, molecular structure, NBO analysis and vibrational spectral analysis of l-tartaric acid single crystal.
Physico chemical properties of L-asparagine L-tartaric acid single crystals: a new nonlinear optical material.
Subchronic and reproductive/developmental (screening level) toxicity of complexation products of iron trichloride and sodium tartrate (FemTA).
Structure elucidation of host-guest complexes of tartaric and malic acids by quasi-racemic crystallography.
Enantioseparation of tartaric acid by ligand-exchange capillary electrophoresis using contactless conductivity detection.
Evidence of metabolic switching and implications for food safety from the phenome(s) of Salmonella enterica serovar Typhimurium DT104 cultured at selected points across the pork production food chain.
Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid.
Monolayer behavior of asymmetrical ester-type tartaric gemini amphiphiles.
Hexavalent chromium reduction in solution and in chromite ore processing residue-enriched soil by tartaric Acid with isopropyl alcohol and divalent manganese as co-reductants.
Additives promote Noyori-type reductions of a β-keto-γ-lactam: asymmetric syntheses of serotonin norepinephrine reuptake inhibitors.
Synthesis of substituted hydantoins in low melting mixtures.
Polyhydroxylated pyrrolizidine alkaloids from transannular iodoaminations: application to the asymmetric syntheses of (-)-hyacinthacine A1, (-)-7a-epi-hyacinthacine A1, (-)-hyacinthacine A2, and (-)-1-epi-alexine.
Optimization of the selective preparation of 20(R)-ginsenoside Rg3 catalyzed by d, l-tartaric acid using response surface methodology.
Fast dissolving eutectic compositions of curcumin.
Expression and production of recombinant cis-epoxysuccinate hydrolase in Escherichia coli under the control of temperature-dependent promoter.
Measurements of thermodynamic and optical properties of selected aqueous organic and organic-inorganic mixtures of atmospheric relevance.
Supramolecular chirality in organo-, hydro-, and metallogels derived from bis-amides of L-(+)-tartaric acid: formation of highly aligned 1D silica fibers and evidence of 5-c net SnS topology in a metallogel network.
Resorcinarene-based cavitands with chiral amino acid substituents for chiral amine recognition.
Efficiency and stability enhancement of cis-epoxysuccinic acid hydrolase by fusion with a carbohydrate binding module and immobilization onto cellulose.
Ion chromatographic separation of inorganic ions using a combination of hydrophilic interaction chromatographic column and cation-exchange resin column.
Hydrochloride salt co-crystals: preparation, characterization and physicochemical studies.
Enantioseparation of racemic mixtures based on solvent sublation.
Crystal engineering of stable temozolomide cocrystals.
High yield recombinant expression, characterization and homology modeling of two types of cis-epoxysuccinic acid hydrolases.
Structural, vibrational and thermal studies of a new nonlinear optical material: L-asparagine-L-tartaric acid.
Amphiphilic Schiff base organogels: metal-ion-mediated chiral twists and chiral recognition.
Bis(imidazolium) L-tartrate: a hydrogen-bonded displacive-type molecular ferroelectric material.
[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-di-yl]bis-[N-(thio-phen-2-yl-methyl-idene)methanamine].
Synthesis of chiral and modifiable hexahydroxydiphenoyl compounds.
Production of starch with antioxidative activity by baking starch with organic acids.
Construction of hydrogen-bonded ternary organic crystals derived from L-tartaric acid and their application to enantioseparation of secondary alcohols.
Active site analysis of cis-epoxysuccinate hydrolase from Nocardia tartaricans using homology modeling and site-directed mutagenesis.
Determination of tafenoquine in dried blood spots and plasma using LC and fluorescence detection.
Homochiral frameworks formed by reactions of lanthanide ions with a chiral antimony tartrate secondary building unit.
Investigation of the low-frequency vibrations of crystalline tartaric acid using terahertz spectroscopy and solid-state density functional theory.
Bis(tetra-ethyl-ammonium) bis-(hydrogen l-tartrate) l-tartaric acid monohydrate.
The role of light in the regulation of ascorbate metabolism during berry development in the cultivated grapevine Vitis vinifera L.
Chiral donor photoinduced-electron-transfer (d-PET) boronic acid chemosensors for the selective recognition of tartaric acids, disaccharides, and ginsenosides.
Reactive electrospinning and biodegradation of cross-linked methacrylated polycarbonate nanofibers.
Effects of hydrophobic chain length on temperature dependence of monolayer behavior of ester-type tartaric geminis.
Mild and expedient asymmetric reductions of α,β-unsaturated alkenyl and alkynyl ketones by TarB-NO2 and mechanistic investigations of ketone reduction.
High-performance liquid chromatographic enantioseparation of (R,S)-fluoxetine using Marfey's reagent and (S)-N-(4-nitrophenoxycarbonyl) phenylalanine methoxyethyl ester as chiral derivatizing reagents along with direct thin-layer chromatographic resolution and isolation of enantiomers using L-tartaric acid as mobile phase additive.
Total regioselective control of tartaric acid.
Synthesis of Biodegradable Amphiphilic Y-shaped Block Co-polymers via Ring-Opening Polymerization for Drug Delivery.
Phenyl-ring rotational disorder in the two-dimensional hydrogen-bonded structure of the 1:1 proton-transfer salt of the diazo-dye precursor 4-(phenyldiazenyl)aniline (aniline yellow) with L-tartaric acid.
HPLC and TLC enantioseparation of the nitro-positioned aryloxysubstituted aminopropanols.
Metal(II)-ligand molar ratio dependence of enantioseparation of tartaric acid by ligand exchange CE with Cu(II) and Ni(II)-D-quinic acid systems.
Three-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of L-tartaric acid with the associative-group monosubstituted pyridines 3-aminopyridine, 3-carboxypyridine (nicotinic acid) and 2-carboxypyridine (picolinic acid).
l-Asparagine-l-tartaric acid (1/1).
The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors.
Phase selection and energetics in chiral alkaline Earth tartrates and their racemic and meso analogues: synthetic, structural, computational, and calorimetric studies.
Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8.
On the interactions of alkyl 2-hydroxycarboxylic acids with alkoxysilanes 2. Complexation and esterification of di- and tricarboxylic acids.
Synthesis, conformation and chiroptical properties of diaryl esters of tartaric acid.
[Phosphatase activity in Amoeba proteus at low pH].
Synthesis of a novel, optically active uridine analog containing a 1,4-dioxane sugar moiety. Synthesis of the corresponding dinucleotide.
Freeze-drying of proteins in glass solids formed by basic amino acids and dicarboxylic acids.
Sorption of tartrate ions to lanthanum (III)-modified calcium fluor- and hydroxyapatite.
Separation and determination of nitroaniline isomers by capillary zone electrophoresis with amperometric detection.
Enantiopure quaternary alpha-trifluoromethyl-alpha-alkoxyaldehydes from L-tartaric acid derived ketoamides.
Functionalized polycarbonate derived from tartaric acid: enzymatic ring-opening polymerization of a seven-membered cyclic carbonate.
Quantitative reconstruction of the nonvolatile sensometabolome of a red wine.
Highly fluorescent supramolecular gels with chirality transcription through hydrogen bonding.
Direct enantiomeric TLC resolution of dl-penicillamine using (R)-mandelic acid and l-tartaric acid as chiral impregnating reagents and as chiral mobile phase additive.
Uptake of glyoxal by organic and Inorganic aerosol.
Direct TLC resolution of atenolol and propranolol into their enantiomers using three different chiral selectors as impregnating reagents.
Application of partial least square on quantitative analysis of L-, D-, and DL-tartaric acid by terahertz absorption spectra.
Synthesis of a bicyclic delta-amino acid as a constrained Gly-Asn dipeptide isostere.
Comparison of a tartaric acid derived polymeric MRI contrast agent to a small molecule model chelate.
Intramolecular Diels-Alder/Tsuji allylation assembly of the functionalized trans-decalin of salvinorin A.
Contribution of wine components to inactivation of food-borne pathogens.
Enhancement of bioavailability and anthelmintic efficacy of albendazole by solid dispersion and cyclodextrin complexation techniques.
Control of oenological products: discrimination between different botanical sources of L-tartaric acid by isotope ratio mass spectrometry.
Chiral separation of sympathomimetics and beta-blockers by ligand-exchange CE using Cu(II) complexes of L-tartaric acid and L-threonine as chiral selectors.
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes.
Chirality induction and protonation-induced molecular motions in helical molecular strands.
Enantiodivergent synthesis of both enantiomers of gypsy moth pheromone disparlure.
Sulfate--a candidate for the missing essential factor that is required for the formation of protein haze in white wine.
Enzyme-mediated preparation of the enantiomerically enriched isomers of the odorous tetrahydropyranyl acetates Jasmal and Jessemal, and their olfactory evaluation.
Computer aided boar semen motility analysis for cereulide detection in different food matrices.
Proton-transfer and non-transfer in compounds of quinoline and quinaldic acid with L-tartaric acid.
Ascorbate as a biosynthetic precursor in plants.
Recovery of metals from Cuban nickel tailings by leaching with organic acids followed by precipitation and magnetic separation.
Total synthesis and stereochemistry of the antitumor antibiotic PD 113,271.
Cloning, sequencing, and expression of a novel epoxide hydrolase gene from Rhodococcus opacus in Escherichia coli and characterization of enzyme.
[Determination of alkaloids in cigarettes by capillary zone electrophoresis].
Modification of the membrane-bound glucose oxidation system in Gluconobacter oxydans significantly increases gluconate and 5-keto-D-gluconic acid accumulation.
High-yield 5-keto-D-gluconic acid formation is mediated by soluble and membrane-bound gluconate-5-dehydrogenases of Gluconobacter oxydans.
Brucine salts of L-alpha-hydroxy acids: brucinium hydrogen (S)-malate pentahydrate and anhydrous brucinium hydrogen (2R,3R)-tartrate at 130 K.
Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives.
A simple method of synthesis of (+/-)-2,3-diarylpiperazines and a novel method of resolution of (+/-)-2,3-diphenylpiperazine.
Differences in motor activation of voluntary and reflex cough in humans.
L-tartaric acid synthesis from vitamin C in higher plants.
Double-headed acyclo C-nucleoside analogues. Functionalized 1,2-bis-(1,2,4-triazol-3-yl)ethane-1,2-diol.
Rapid inorganic ion analysis using quantitative microchip capillary electrophoresis.
Thermodynamic and spectroscopic studies of copper (II) complexes with three bis(amide) ligands derived from L-tartaric acid.
Continuous production of L(+)-tartaric acid from cis-epoxysuccinate using a membrane recycle reactor.
An efficient kinetic resolution of racemic Betti base based on an enantioselective N,O-deketalization.
Oral bioavailability in pigs of a miconazole/hydroxypropyl-gamma-cyclodextrin/L-tartaric acid inclusion complex produced by supercritical carbon dioxide processing.
New concise total synthesis of (+)-lentiginosine and some structural analogues.
L-Tartaric acid assisted binary organogel system: strongly enhanced fluorescence induced by supramolecular assembly.
13C and 18O isotopic analysis to determine the origin of L-tartaric acid.
Enhanced fluorescence and chiral discrimination for tartaric acid in a dual fluorophore boronic acid receptor.
A Gluconobacter oxydans mutant converting glucose almost quantitatively to 5-keto-D-gluconic acid.
Synthesis and stereochemistry of musacins isolated from Streptomyces griseoviridis(FH-S 1832).
Effect of acidic ternary compounds on the formation of miconazole/cyclodextrin inclusion complexes by means of supercritical carbon dioxide.
Enantioseparation of amino acid derivatives on an immobilized network polymer derived from L-tartaric acid.
Retardation of setting of plaster of Paris by organic acids: understanding the mechanism through molecular modeling.
Cholinesterase and phosphatase activities in adults and infective-stage larvae of levamisole-resistant and levamisole-susceptible isolates of Haemonchus contortus.
Hydrogel patches containing triclosan for acne treatment.
Aldol reactions of dioxanes derived from tartaric acid. A total synthesis of (+)-nephrosteranic acid.
Biotransformation of glucose to 5-keto-D-gluconic acid by recombinant Gluconobacter oxydans DSM 2343.
A novel left-handed double helicate constructed from L-tartrate bridged molybdenum(vi) and gadolinium(iii) atoms.
Effect of tartaric acid-induced cough on pulmonary function in normal and asthmatic humans.
Enantiomeric separations of amino alcohols by packed-column SFC on Hypercarb with L-(+)-tartaric acid as chiral selector.
Improvement of physicochemical properties of N-4472. Part III. VC/N-4472 complex formation and self-association in aqueous solution.
Stereoselective metabolism of pentoxifylline in vitro and in vivo in humans.
Total synthesis of (-)- and (+)-lentiginosine.
Stereoselective radical reactions of some tartaric and glyceric acid derivatives.
Use of disposable GRC electrodes for the detection of phenol and chlorophenols in liquid chromatography.
Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides.
The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions.
Direct chiral resolution of malic acid in apple juice by ligand-exchange capillary electrophoresis using copper(II)-L-tartaric acid as a chiral selector.
[Study on the improvement of process technology of L(+)-tartaric acid fermentation].
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.
Malo-ethanolic fermentation in grape must by recombinant strains of Saccharomyces cerevisiae.
Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors.
Direct resolution of (+/-)-ephedrine and atropine into their enantiomers by impregnated TLC.
Hydrogen-bonded complexes of 2-pyridone with centrosymmetric and non-centrosymmetric dicarboxylic acids.
Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat.
Entropy-controlled selectivity in the vinylation of a cyclic chiral nitrone. An efficient route to enantiopure polyhydroxylated pyrrolidines.
A high-performance liquid chromatographic assay for the determination of desbutylhalofantrine enantiomers in rat plasma.
An efficient and convenient approach to the total synthesis of sphingofungin.
[Production of L(+)-tartaric acid by immobilized Corynebacterium sp. JZ-1].
Candida tartarivorans sp. nov., an anamorphic ascomycetous yeast with the capacity to degrade L(+)- and meso-tartaric acid.
Calcium pectate gel beads for cell entrapment. 6. Morphology of stabilized and hardened calcium pectate gel beads with cells for immobilized biotechnology.
Experimental and theoretical analysis of the interaction of (+/-)-cis-ketoconazole with beta-cyclodextrin in the presence of (+)-L-tartaric acid.
Stereoselective total synthesis of (3R,8S)-falcarindiol, a common polyacetylenic compound from umbellifers
Structure-activity relationships: analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication.
Stereoisomers of cyclic urea HIV-1 protease inhibitors: synthesis and binding affinities.
Cytoplasmic membrane lipoprotein LppC of Streptococcus equisimilis functions as an acid phosphatase.
Influence of D(-) and L(+) tartaric acid on lysozyme adsorption onto a Si(Ti)-O2 surface.
Preparation and structure-activity relationship of novel P1/P1'-substituted cyclic urea-based human immunodeficiency virus type-1 protease inhibitors.
[Synthesis of estimated metabolites of 9-amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinoline monohydrochloride monohydrate (NIK-247). II. Synthesis of dihydroxylated metabolites].
A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma.
Simultaneous determination of urinary creatinine, calcium and other inorganic cations by capillary zone electrophoresis with indirect ultraviolet detection.
Specific transfer of 3H from D-[3-3H]gluconic acid into L-tartaric acid in vitaceous plants.
[Splenic lymphoma with circulating villous lymphocytes. Study of 6 patients].
Enantioselective antiplatelet actions of nipecotamides.
[Stereoisomers of 3-methylfentanyl: synthesis, absolute configuration and analgesic activity].
Morphological and cytochemical characteristics of atypical mononuclear cells in the blood of patients with the syndrome of infectious mononucleosis caused by Epstein-Barr virus.
Utilization of tartaric acid and related compounds by yeasts: taxonomic implications.
Active principle of swine prostate extract: I. Isolation of active principle activating prostatic acid phosphatase and its effect on testosterone uptake of the prostate in castrated rats.
[Separation and resolution of four stereo-isomers of anisodamine].
Transport of malic acid and other dicarboxylic acids in the yeast Hansenula anomala.
Imidazo[2,1-b]benzothiazoles. II. Synthesis and antiinflammatory activity of some imidazo[2,1-b]benzothiazoles.
Leucosporidium fellii sp. nov., a basidiomycetous yeast that degrades L(+)-tartaric acid.
Tartrate-resistant acid phosphatase in bone and cartilage following decalcification and cold-embedding in plastic.
The influence of optical design on the signal to noise characteristics of polarimeters.
Probes for narcotic receptor mediated phenomena. 12. cis-(+)-3-Methylfentanyl isothiocyanate, a potent site-directed acylating agent for delta opioid receptors. Synthesis, absolute configuration, and receptor enantioselectivity.
Genetic variation of an acid phosphatase (Acp-2) in the laboratory rat: possible homology with mouse AP-1 and human ACP2.
Synthesis of l-(+)-Tartaric Acid from l-Ascorbic Acid via 5-Keto-d-Gluconic Acid in Grapes.
The stability of prostatic acid phosphatase, as measured by a capture immunoenzyme assay.
Regulation of metabolism in Penicillium charlesii by organic acids: role of L-tartaric acid.
A cleavable cross-linking reaction for protein carboxyl groups.
Biosynthesis and metabolism of L-ascorbic acid in virginia creeper (Parthenocissus quinquefolia L.).
[Hairy cell leukemia: pathomorphology, cytology and cytochemistry].
Light and electron microscope histochemistry of alkaline phosphatase in the ventral prostate of rats.
Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine.
Selective purification of tartrate-inhibitable acid phosphatases: rapid and efficient purification (to homogeneity) of human and canine prostatic acid phosphatases.
The cytochemistry of tartrate-resistant acid phosphatase. Technical considerations.
Multiple forms of acid phosphatase activity in Gaucher's disease.
Metabolism of L(+)-and D(-)-tartaric acids in different animal species.
Absorption and biotransformation of L(+)-tartaric acid in rats.
To enzyme analogues by lock and key chemistry with crown compounds. Part 1. Enantiomeric differentiation by configurationally chiral cryptands synthesised from L-tartaric acid and D-mannitol.
TARTARIC ACID METABOLISM. I. SUBUNITS OF L(+)-TARTARIC ACID DEHYDRASE.
REVERSIBLE DISSOCIATION OF L-TARTARIC ACID DEHYDRASE INTO SUBUNITS.
Serum-total and L()-tartaric-acid inhibited acid-phosphatase activity in various diseases in childhood.
Tartaric acid metabolism of Neurospora crassa.
[Research on the phosphatase of the prostate. II. Study of the inhibitory action of L(+) tartaric acid].
EXPERIMENTS ON ANAPHYLAXIS TO AZOPROTEINS : THIRD PAPER.

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
FDA Indirect Additives used in Food Contact Substances:	View
CHEBI:	View
CHEMBL:	View
Golm Metabolome Database:	Search
Metabolomics Database:	Search
KEGG (GenomeNet):	C00898
HMDB (The Human Metabolome Database):	HMDB00956
FooDB:	FDB001113
YMDB (Yeast Metabolome Database):	YMDB01788
Export Tariff Code:	2918.12.0000
FDA Listing of Food Additive Status:	View
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View
FAO:	L(+)-TARTARIC ACID
FAO:	Tartaric acid (+)-, (-)-, (+/-)-, meso-

Suppliers

American International Chemical, LLC.	BOC Sciences
Charkit Chemical	ECSA Chemicals
ExtraSynthese	Foodchem International
Glentham Life Sciences	Indenta Group
Lluch Essence	Meafo
Penta International	Prinova
Reincke & Fichtner	Shiva Chemicals and Pharmaceuticals
TCI AMERICA	Tianjin Talent Chemical
American International Chemical, Inc.	Charkit Chemical Corporation
Glentham Life Sciences Ltd	Lluch Essence S.L.
Penta International Corporation

PhysChem Properties

Material listed in food chemical codex	Yes
Molecular weight	150.08702087402
Melting Point	170 to 172°C @ 760 mm Hg
Vapor Density	5.18
Flash Point TCC Value	150 °C TCC
logP (o/w)	-1.426 est
Solubility
alcohol	Yes
water, 5.82E+05 mg/L @ 20 °C (exp)	Yes

Organoleptic Properties

Odor Type: Odorless
Odor strength	none
General comment	At 100.00 %. odorless
Flavor Type: Acidic
tart, acidic
General comment	Tart acidic

Occurrences

Potential Uses

Applications	firming agents flavor enhancers flavoring agents humectants pH control agents
Other purposes	Buffering agents
Cosmetic purposes	Buffering agents, Fragrance

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-dog LDLo 5000 mg/kg Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 275, 1950. intravenous-mouse LD50 485 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: HEMORRHAGE Journal of Agricultural and Food Chemistry. Vol. 5, Pg. 759, 1957. oral-rabbit LDLo 5000 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Industrial and Engineering Chemistry. Vol. 15, Pg. 628, 1923. oral-rat LDLo 7500 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES National Technical Information Service. Vol. OTS0555808
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
firming agents, flavor enhancers, flavoring agents, humectants, pH control agents
Recommendation for laevo-(+)-tartaric acid usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		-	1300.00000
beverages(nonalcoholic):		-	960.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	3700.00000
condiments / relishes:		-	10000.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	570.00000
fruit ices:		-	570.00000
gelatins / puddings:		-	60.00000
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	5400.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety references

European Food Safety Authority (EFSA) reference(s):

Re-evaluation of l(+)-tartaric acid (E 334), sodium tartrates (E 335), potassium tartrates (E 336), potassium sodium tartrate (E 337) and calcium tartrate (E 354) as food additives
View page or View pdf

Re-evaluation of acetic acid, lactic acid, citric acid, tartaric acid, mono- and diacetyltartaric acid, mixed acetic and tartaric acid esters of mono- and diglycerides of fatty acids (E 472a-f) as food additives
View page or View pdf

EPI System: View

ClinicalTrials.gov:search

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):87-69-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :444305

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:1