2-methyl-4-(camphenyl-8) cyclohexanone

2-methyl-4-(camphenyl-8) cyclohexanone is a bicyclic ketone compound with the molecular formula C₁₇H₂₈O. It appears as a colorless liquid and is recognized by the trade name aldron, among various synonyms. This synthetic material exhibits a distinctive animalic amber musk odor noted for its powerful diffusion and lasting character. The compound is mainly employed in fragrance and cosmetic applications. Comprehensive chemical data is cataloged under PubChem CID 111416, facilitating research and regulatory compliance. Typically synthesized, it contributes complex nuances to perfume compositions by enhancing woody, tobacco, musk, and incense notes.

While 2-methyl-4-(camphenyl-8) cyclohexanone does not occur naturally, it is applied widely as a fragrance ingredient due to its animalic and woody amber musk scent profile. Its inclusion enhances diffusion and longevity in perfumes, particularly in woody, tobacco, musk, and incense accord blends. The compound aligns with IFRA (Global) standards, guiding usage in fragrance formulations to ensure consumer safety. Its powerful character necessitates cautious dosage, as overuse can overwhelm blends. Overall, it serves as a valuable agent in sophisticated perfumery for imparting depth and complexity.

This bicyclic ketone exhibits a molecular weight of approximately 248.41 g/mol and presents as a moderately dense liquid with a specific gravity ranging from 0.971 to 0.982 at 25 °C. Its refractive index lies between 1.499 and 1.505 at 20 °C, indicating optical properties relevant for quality control. Boiling occurs between 324 and 325 °C at standard atmospheric pressure, while vapor pressure is notably low at 0.000247 mmHg at 25 °C, reflecting low volatility. The estimated logP of 5.361 suggests significant lipophilicity, favoring solubility in alcohols and limited solubility in water. Stability is generally good in formulations such as body lotions, shampoos, and liquid cleaners but poor in bleach-containing products. These properties influence handling, formulation compatibility, and longevity in consumer products.

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Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-methyl-4-(camphenyl-8) cyclohexanone flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):68901-22-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :111416

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

4-[(6,6-dimethyl-5-bicyclo[2.2.1]heptanyl)methyl]-2-methylcyclohexan-1-one

Chemidplus:0068901224