2-methyl-3-(methyl thio) pyrazine

General Material Information

Preferred name	2-methyl-3-(methyl thio) pyrazine
Trivial Name	2-Methyl-3-(methylthio)pyrazine
Short Description	2-methylthio-3-methylpyrazine
Formula	C6 H8 N2 S
CAS Number	2882-20-4
FEMA Number	3208
Flavis Number	14.128
ECHA Number	220-736-8
FDA UNII	KI350CS0LZ
Nikkaji Number	J110.563I
MDL	MFCD00014610
COE Number	2290
Bio Activity Summary	External link
NMR Predictor	External link
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
Synonyms	2-methyl 3-methyl thio pyrazine 2-methyl mercapto-3-methyl pyrazine 2-methyl thio-3-methyl pyrazine 2-( methyl thio)-3-methyl pyrazine 3-methyl-2-methyl thiopyrazine 3-methyl-2-methylthiopyrazine 2-methyl-3-(methyl thio) pyrazine 2-methyl-3-(methylmercapto)pyrazine 2-methyl-3-(methylsulfanyl)pyrazine 2-methyl-3-(methylthio)pyrazine 2-methyl-3-methyl mercaptopyrazine 2-methyl-3-methyl sulfanyl pyrazine 2-methyl-3-methylsulfanylpyrazine 2-methyl-3-methylthiopyrazine 2-methylmercapto-3-methylpyrazine 2-methylthio-3-methyl pyrazine 2-methylthio-3-methylpyrazine 2-( methylthio)-3-methylpyrazine pyrazine, 2-methyl-3-(methylthio)- pyrazine, methyl(methylthio)- 2-methyl-3-methylsulfanylpyrazine 2-Methyl-3-(methylthio)pyrazine 2-Methyl-3-methylmercaptopyrazine 2-Methylthio-3-methylpyrazine 3-Methyl-2-methylthiopyrazine 2-Methylmercapto-3-methylpyrazine NSC 222757 2-Methyl-3-(methylsulfanyl)pyrazine

	2-methyl-3-methylsulfanylpyrazine
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	2882-20-4
Pubchem (cid):	76152
Pubchem (sid):	135033166

Publications by US Patents
3,952,024 - Furfurylthioacetone

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB32384
FooDB:	FDB020200
Export Tariff Code:	2933.99.9700
ChemSpider:	View

Beijing Lys Chemicals	BOC Sciences
Fleurchem	Jiangyin Healthway
Jinan Enlighten Chemical Technology(Wutong Aroma )	Lluch Essence
M&U International	Penta International
R C Treatt & Co Ltd	Santa Cruz Biotechnology
Sigma-Aldrich: Aldrich	Sunaux International
Synerzine	TCI AMERICA
Tengzhou Jitian Aroma Chemiclal	Tengzhou Xiang Yuan Aroma Chemicals
Tianjin Danjun International	Vigon International
WholeChem	Beijing Lys Chemicals Co, LTD.
Fleurchem, Inc.	Jiangyin Healthway International Trade Co., Ltd
Lluch Essence S.L.	M&U International LLC
Penta International Corporation	Synerzine, Inc.
Tianjin Danjun International Trade Co., LTD.	R C Treatt and Co Ltd
WholeChem, LLC

Material listed in food chemical codex	No
Molecular weight	140.20875549316
Specific gravity	@ 25 °C
Pounds per Gallon	9.428 to 9.594
Refractive Index	1.57 to 1.59 @ 20 °C
Boiling Point	85 to 87°C @ 10 mm Hg
Boiling Point	213 to 214°C @ 760 mm Hg
Vapor Pressure	0.163 mmHg @ 25 °C
Flash Point TCC Value	98.89 °C TCC
logP (o/w)	1.81
Solubility
alcohol	Yes
water, 2379 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Nutty
roasted, meaty roasted meaty, nutty, almond, vegetable
General comment	At 0.10 % in propylene glycol. roasted meat nutty almond vegetable

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-methyl-3-(methyl thio) pyrazine usage levels up to:
	0.0200 % in the fragrance concentrate.

Maximised Survey-derived Daily Intakes (MSDI-EU):		0.68 (μg/capita/day)
Threshold of Concern:		90 (μg/person/day)
Structure Class:		III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
Click here to view publication 4
		average usual ppm	average maximum ppm
baked goods:		-	4.00000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	2.00000
fruit ices:		-	2.00000
gelatins / puddings:		-	2.00000
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	2.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-