laevo-camphor

General Material Information

Preferred name	laevo-camphor
Trivial Name	(-)-Camphor
Short Description	bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)-
Formula	C10 H16 O
CAS Number	464-48-2
ECHA Number	207-354-7
FDA UNII	213N3S8275
Beilstein Number	1907612
MDL	MFCD00064148
xLogP3-AA	2.20 (est)
NMR Predictor	External link
Synonyms	(-)- alcanfor bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-, (1S,4S)- bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)- (-)- bornan-2-one (-)-2-bornanone (1S,4S)-(-)- camphor (1S)- camphor (1S)-(-)- camphor L- camphor laevo-(-)- camphor camphor, (1S,4S)-(-)- camphor, L-, (-)- (1S,4R)-(-)-1,3,3-trimethyl bicyclo(2.2.1)heptan-2-one (1S,4S)-1,7,7-trimethyl bicyclo(2.2.1)heptan-2-one (1S)-1,7,7-trimethyl bicyclo(2.2.1)heptan-2-one (1S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (1S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S,4S)- (1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one l-Camphor (-)-Camphor (-)-Alcanfor (1S)-(-)-Camphor (1S)-Camphor (1S,4S)-(-)-Camphor NSC 26351 (S)-(-)-Camphor (1S)-1,7,7-Trimethylbicyclo[2.2.1]-2-heptanone

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Literature & References

Leffingwell:	Chirality or Article
	(1S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	10050
Pubchem (sid):	135269914

Publications by PubMed
Inhibition of cholinesterase by essential oil from food plant.
Topological and experimental approach to the pressure-temperature-composition phase diagram of the binary enantiomer system d- and l-camphor.
Cocrystallization and configurations of myo-inositol-1,2-L-camphor acetals in two crystal structures.
U.v. absorbers in sun cosmetics 1978.
A transmissible plasmid controlling camphor oxidation in Pseudomonas putida.

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
KEGG (GenomeNet):	C00809
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2914.21.2000
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Suppliers

BOC Sciences	EMD Millipore
ExtraSynthese	Santa Cruz Biotechnology
Sigma-Aldrich: Aldrich	TCI AMERICA

PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	152.23672485352
Optical Rotation	-41 to -45
Melting Point	178 to 180°C @ 760 mm Hg
Vapor Pressure	0.04 mmHg @ 20 °C
Vapor Density	5.24
Flash Point TCC Value	65 °C TCC
logP (o/w)	2.089 est
Solubility
alcohol	Yes
water, 339.1 mg/L @ 25 °C (est)	Yes
water	No

Organoleptic Properties

Odor Type: Camphoreous
camphoreous
General comment	At 10.00 % in dipropylene glycol. camphor

Occurrences

Potential Uses

Applications	flavor and fragrance agents
Odor purposes	Acacia, Agate, Agrumen aldehyde, Ajowan, Allspice, Allspice, Alpine bouquet, Angelica, Arnica flower, Ash mountain ash berry, Basil oil replacer, Bay rum, Bayberry, Bayberry, Blue grass, Cajeput, Calamus oil replacer, Camphor tree bark, Caraway seed, Cardamom oil replacer, Carnation, Carrot seed, Cassia, Cassia blossom, Celery, Chamomile, Chrysanthemum, Cilantro, Cinnamon, Clary sage oil replacer, Clove, Copaiba balsam, Coriander, Country meadow, Cranberry, Croton eluteria bark, Cubeb, Cumin oil replacer, Currant bud absolute replacer, Curry leaf, Cypress oil replacer, Deertongue absolute replacer, Dill weed, Dogwood, Elder flower, Eucalyptus oil replacer, Fennel, Fig, Flouve, Forest, Galangal root, Genet, Geranium, Ginger, Ginger white ginger, Gingerbread, Gingergrass, Graham cracker, Guaiacwood, Habuba, Heather, Herbal, Hinoki oil replacer, Hollyberry, Hop, Hyssop, Ivy, Jonquil, Lavandin, Lavender, Lavender flower, Lavender spike lavender, Lovage root, Mace, Maja, Marigold, Marjoram, Melissa oil replacer, Mimosa, Myrrh, Myrtle oil replacer, Niaouli, Nutmeg, Oregano, Osmanthus, Parsley leaf, Pepper, Pepper black pepper, Pepper tree berry, Pine forest, Pine needle, Pizza, Pumpkin pie, Reseda, Root beer, Rose dog rose, Rose moss rose, Rosemary, Rue, Saffron, Sassafras, Savin, Snake root, Spice, Spicewood, Spikenard oil replacer, Spruce, Sweet grass, Tansy oil replacer, Tea green tea, Thyme oil white replacer, Tolu balsam, Valerian, Witch hazel, Woodruff, Wormwood oil replacer, Yerba mate, Yew
Flavoring purposes	Absinthe, Ajowan, Angelica, Buchu leaf, Cajeput, Camphor tree bark, Capsicum, Caraway seed, Carrot, Carrot seed, Chervil, Cilantro, Copaiba balsam, Coriander, Croton eluteria bark, Cubeb, Currant bud absolute replacer, Curry leaf, Dill weed, Galangal root, Gin, Guaiacwood, Hyssop, Lavender flower, Lavender spike lavender, Lovage root, Marigold, Marjoram, Mustard, Parsley leaf, Pepper black pepper, Pepper tabasco pepper, Pepper tree berry, Pine needle, Rue, Sarsaparilla, Savin, Snake root, Tansy oil replacer, Tea, Tea black tea, Tea black tea, Tea herbal tea, Tea lemon tea, Valerian, Wasabi, Worcestershire sauce, Yerba mate
Other purposes	Boldus oil replacer, Parsnip, Pepper chili pepper, Tea china, Watercress nasturtium

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 0.80 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 1, Pg. 445, 1909. intravenous-mouse LD50 320 mg/kg Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02534 intravenous-mouse LD50 320 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02534 oral-rat LDLo 800 ug/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 1, Pg. 445, 1909.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for laevo-camphor usage levels up to:
	5.0000 % in the fragrance concentrate.

Safety references

European Food Safety Authority (EFSA) reference(s):

Camphor in flavourings and other food ingredients with flavouring properties - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):464-48-2

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :10050

National Institute of Allergy and Infectious Diseases:Data

WISER:UN 2717

WGK Germany:1

(1S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one