clover nitrile

Clover nitrile, also known by synonyms including Butylphenylacetonitrile, alpha-butyl benzene acetonitrile, and salicynalva (IFF), is an organic compound with the molecular formula C₁₂H₁₅N. It typically appears as a synthetic fragrance agent characterized by a balsamic, clover-like odor with moderate intensity. This medium-strength aroma combines notes reminiscent of orchids, narcissus, and styrax, rendering it valuable in perfumery. The compound is catalogued under PubChem CID 97799, providing detailed chemical and structural information. Developed for aromatic applications, clover nitrile is manufactured primarily through synthetic organic processes rather than extraction from natural sources.

Clover nitrile is not known to occur naturally in biological systems but is widely utilized as a fragrance component due to its distinctive balsamic and floral odor profile. Its application spans various fragrance products including perfumes, colognes, and personal care items where a clover, orchid, or balsam note is desired. The compound aligns with fragrance standards such as those set by IFRA (International Fragrance Association, Global), which governs its usage limits to ensure safety and stability in formulations. While primarily used in perfumery, trace usage in flavoring is not recommended. Its olfactory versatility supports blending with aldehydic, floral, fruity, and woody notes, broadening its functional potential.

Clover nitrile presents as a moderately lipophilic molecule with an estimated log P around 3.5, indicating a preference for organic solvents over aqueous media. It has a boiling point near 272–273 °C at standard atmospheric pressure, denoting relatively low volatility at room temperature. Vapor pressure is low, approximately 0.006 mmHg at 25 °C, contributing to its substantivity in fragrance applications. Solubility is noted as good in alcohols, consistent with typical perfumery solvents, although limited in pure water at around 36 mg/L at 25 °C. The flash point is approximately 212 °F (100 °C), informing handling and storage requirements. Stability assessments indicate compatibility with common cosmetic and cleaning product formulations including lotions, shampoos, and detergents.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
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(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2926.90.0000
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Safety information

European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for clover nitrile usage levels up to:
	20.0000 % in the fragrance concentrate.
Recommendation for clover nitrile flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):3508-98-3

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :97799

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

2-phenylhexanenitrile

Chemidplus:0003508983