(E)-isoeugenol

General Material Information

Preferred name	(E)-isoeugenol
Trivial Name	trans-Isoeugenol
Short Description	trans-p-propenylguaiacol
Formula	C10 H12 O2
CAS Number	5932-68-3
ECHA Number	227-678-2
FDA UNII	28FSR1NAY4
Nikkaji Number	J53.761F
Beilstein Number	2046156
MDL	MFCD00009285
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	(E)-iso eugenol trans-iso eugenol iso eugenol E iso eugenol trans-form iso eugenol, (E)-isomer 2-methoxy-4-((E)-propenyl)-phenol trans-2-methoxy-4-(1-propenyl)phenol (E)-2-methoxy-4-(prop-1-en-1-yl)phenol (E)-2-methoxy-4-(prop-1-enyl) phenol trans-2-methoxy-4-(prop-1-enyl) phenol (E)-2-methoxy-4-(prop-1-enyl)phenol 2-methoxy-4-[(1E)-1-propen-1-yl]phenol 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol 2-methoxy-4-[(E)-prop-1-enyl]phenol (E)-2-methoxy-4-propenyl phenol trans-2-methoxy-4-propenyl phenol trans-2-methoxy-4-propenylphenol phenol, 2-methoxy-4-(1-propenyl)-, (E)- (E)-p- propenyl guaiacol (E)-para- propenyl guaiacol trans-p- propenyl guaiacol trans-para- propenyl guaiacol (E)-para- propenylguaiacol trans-p- propenylguaiacol trans-para- propenylguaiacol (E)-p- propenylquaiacol trans-p- propenylquaiacol 2-methoxy-4-[(E)-prop-1-enyl]phenol Phenol, 2-methoxy-4-(1E)-1-propen-1-yl- Phenol, 2-methoxy-4-propenyl-, (E)- Phenol, 2-methoxy-4-(1E)-1-propenyl- 2-Methoxy-4-(1E)-1-propen-1-ylphenol trans-Isoeugenol trans-p-Propenylguaiacol trans-2-Methoxy-4-(1-propenyl)phenol 2-Methoxy-4(E)-1-propenylphenol NSC 209522 2-Methoxy-4-[(1E)-1-propenyl]phenol (E)-2-Methoxy-4-(1-propenyl)phenol 2-Methoxy-4-[(E)-1-propenyl]phenol trans-4-Propenylguaiacol (E)-2-Methoxy-4-(prop-1-en-1-yl)phenol

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Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
KEGG (GenomeNet):	C10469
HMDB (The Human Metabolome Database):	HMDB05802
FooDB:	FDB012403
YMDB (Yeast Metabolome Database):	YMDB01677
Export Tariff Code:	2909.50.4010
Typical G.C.
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Suppliers

Sigma-Aldrich

PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	164.20404052734
Melting Point	32 to 34°C @ 760 mm Hg
Boiling Point	266 to 268°C @ 760 mm Hg
Vapor Pressure	0.005 mmHg @ 25 °C
Flash Point TCC Value	122.78 °C TCC
logP (o/w)	2.451 est
Solubility
alcohol	Yes
water, 165.9 mg/L @ 25 °C (est)	Yes
water	No

Organoleptic Properties

Odor Type: Spicy
sweet, spicy, carnation, phenolic, floral
Luebke, William tgsc, (1985)	At 100.00 %. sweet spicy carnation phenolic floral

Occurrences

Potential Uses

Applications	fragrance agents
Odor purposes	Carnation, Clove, Spice
Cosmetic purposes	Perfuming agents

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 540 mg/kg Chem-Fleur, Inc. intraperitoneal-mouse LD50 540 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 815, 1975.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Sensitization
limits in the finished product for - "leave on the skin contact":
	0.0200 % Restriction.
limits in the finished product for - "wash off the skin contact":
	0.0200 % Restriction.
limits in the finished product for - "no skin contact":
	0.2000 % Restriction.
Recommendation for (E)-isoeugenol usage levels up to:
	2.0000 % in the fragrance concentrate.

Recommendation for (E)-isoeugenol flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :853433

National Institute of Allergy and Infectious Diseases:Data

SCCNFP:opinion

WGK Germany:2

2-methoxy-4-[(E)-prop-1-enyl]phenol

Chemidplus:0005932683