sandal pentenol

Sandal pentenol, also known by its preferred name and synonyms such as ebanol and muscosandrol, is an organic compound with the molecular formula C₁₄H₂₄O. This compound appears as a colorless to pale yellow liquid with a distinctive woody musk odor reminiscent of natural sandalwood. Its chemical structure features a cyclopentene ring with methyl substitutions and an alcohol functional group, giving it specific olfactive properties. Sandal pentenol serves primarily as a synthetic fragrance or flavoring agent and is chemically identified with CAS number 67801-20-1. It is commonly sourced via chemical synthesis for use in perfumery and flavor formulations to imitate or enhance sandalwood accords. For detailed chemical information, the compound is indexed in authoritative databases such as PubChem.

Sandal pentenol does not naturally occur in significant quantities but is produced synthetically to replicate sandalwood aroma notes. It is extensively utilized in the flavor and fragrance industry to impart a rich, woody, and musky sandalwood scent to perfumes, personal care products, and fine fragrances. The compound integrates well with various woody and floral accords, enhancing complexity and diffusion. Its applications extend to flavoring agents where it can contribute subtle woody or herbal nuances, including notes reminiscent of cistus, galangal root, and guaiacwood. Sandal pentenol’s use is regulated with adherence to the IFRA (Global) Code of Practice, which limits its concentration to a maximum of 5% in fragrance concentrates to ensure safe application in consumer products.

Sandal pentenol exhibits moderate volatility with a boiling point around 287 to 288 °C at atmospheric pressure, and a very low vapor pressure of approximately 0.000281 mmHg at 25 °C, supporting its high substantivity in fragrance compositions. It has an estimated logP value of 4.429, indicating lipophilic characteristics favoring solubility in alcohol and limited solubility in water (around 35 mg/L at 20 °C). The refractive index ranges from 1.478 to 1.484 at 20 °C, and the specific gravity varies between 0.898 and 0.904 at 25 °C. Its flash point is measured at 212 °F, emphasizing careful handling during formulation. Sandal pentenol demonstrates good stability in alcoholic solutions, powders, soaps, and dry or damp fabrics, with moderate stability in alkaline conditions (pH 10) and antiperspirant sprays, while showing poor stability in liquid bleach. These properties influence its performance in diverse product types, ensuring a durable woody note with enhanced diffusion and lasting character.

Leffingwell:	Chirality or Article
	(Z)-3-methyl-5-(2,2,3-trimethyl-1-cyclopent-3-enyl)pent-4-en-2-ol
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6437266
Pubchem (sid):	135063422
	(E)-3-methyl-5-(2,2,3-trimethyl-1-cyclopent-3-enyl)pent-4-en-2-ol
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6504499
Pubchem (sid):	37905155

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 5000 mg/kg Description from Givaudan: “Ebanol has a very rich, natural sandalwood odour. It is powerful and intense, bringing volume and elegance to woody accords and a diffusive sandalwood effect to compositions. Ebanol is highly substantive on all supports.”
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for sandal pentenol usage levels up to:
	5.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 26
Click here to view publication 26
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		0.10000	1.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		0.10000	1.00000
chewing gum:		1.00000	10.00000
condiments / relishes:		-	-
confectionery froastings:		0.10000	5.00000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		0.10000	5.00000
imitation dairy:		-	-
instant coffee / tea:		0.10000	1.00000
jams / jellies:		0.10000	1.00000
meat products:		-	-
milk products:		0.10000	1.00000
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		10.00000	100.00000
snack foods:		-	-
soft candy:		0.10000	5.00000
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):67801-20-1

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6437266

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

(Z)-3-methyl-5-(2,2,3-trimethyl-1-cyclopent-3-enyl)pent-4-en-2-ol

Chemidplus:0067801201

(E)-3-methyl-5-(2,2,3-trimethyl-1-cyclopent-3-enyl)pent-4-en-2-ol