2,5,7-trimethyl-5,7-dihydrofuro-[3,4-d]-pyrimidine

2,5,7-trimethyl-5,7-dihydrofuro-[3,4-d]-pyrimidine is a heterocyclic chemical compound with the molecular formula C₉H₁₂N₂O. It typically appears as a colorless to pale substance and features a distinct sweet cereal odor and flavor profile. This compound belongs to the chemical class of fused heterocycles involving furan and pyrimidine rings. Synonyms include 2,5,7-trimethyl-5,7-dihydrofuro[3,4-d]pyrimidine, and its structure and properties are documented in public scientific databases such as PubChem. It is obtained primarily through synthetic chemical processes rather than natural extraction due to its specialized structure. The compound is noted for its sweet cereal sensory qualities, though it is not widely used in commercial fragrance or flavor applications.

This compound does not naturally occur in significant biological sources or food materials. Its primary relevance lies in chemical research related to heterocyclic compounds. Application is limited to informational contexts, as it is not employed in fragrance or flavor formulations. Regulatory authorities such as REACH (European Union) recognize substances with detailed data to ensure safe usage; however, 2,5,7-trimethyl-5,7-dihydrofuro-[3,4-d]-pyrimidine is not registered for commercial use in consumer products. This designation indicates its status as a chemical of interest mainly for study and documentation, rather than practical application in sensory goods.

The compound's estimated partition coefficient (xlogP) is approximately 0.70, indicating moderate lipophilicity. It has a molecular weight of 164.21 g/mol and exhibits solubility in water at about 8331 mg/L at 25°C, suggesting good aqueous solubility. These properties contribute to predictable behavior in formulation systems, although its limited practical use confines its consideration to theoretical or experimental settings. The fused ring structure combines oxygen and nitrogen heteroatoms, which can influence stability and potential reactivity. Overall, the physico-chemical profile points to a stable, water-soluble molecule with mild hydrophobic character due to methyl substitutions.

	2,5,7-trimethyl-5,7-dihydrofuro[3,4-d]pyrimidine
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	21554593
Pubchem (cas):	NF0631

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for 2,5,7-trimethyl-5,7-dihydrofuro-[3,4-d]-pyrimidine usage levels up to:
	not for fragrance use.
Recommendation for 2,5,7-trimethyl-5,7-dihydrofuro-[3,4-d]-pyrimidine flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

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Toxicology Citations:Search

Laboratory Chemical Safety Summary :21554593

2,5,7-trimethyl-5,7-dihydrofuro[3,4-d]pyrimidine