1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)octane

1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)octane is a bicyclic organic compound characterized by a carbomethoxy functional group attached to a bicyclo[2.2.2]octane scaffold with four methyl substituents. It appears as a synthetic chemical with a distinctive multisensory profile, including fruity, green, minty, fig-like, and woody odor nuances when evaluated at a 1.00% dilution in dipropylene glycol. This compound is referenced under synonyms such as 1,3,3,5-tetramethyl-8-carbomethoxybicyclo-[2.2.2]-octane and 1,3,3,5-tetramethyl-8-carbomethoxybicyclo[2.2.2]octane, ensuring consistency in chemical cataloging. While widely documented in chemical repositories like PubChem, it does not currently originate from natural sources but is typically prepared through synthetic organic chemistry methods. It remains primarily of academic and informational interest rather than commercial use.

This compound does not occur naturally and is synthesized for research and informational purposes. It is not employed in fragrance or flavor production, a decision reflected in relevant usage standards and regulatory frameworks such as those outlined by IFRA (Global). Its complex bicyclic structure and odor profile have attracted analytical interest to characterize sensory attributes for potential future applications, but practical formulation uses are not established. The compound’s absence from flavor and fragrance applications aligns with limiting recommendations and scientific safety assessments. It demonstrates sensory properties of potential relevance for chemists exploring novel odorants or bicyclic ester derivatives.

1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)octane exhibits physical and chemical characteristics typical of bicycloalkane esters. Its molecular structure imparts moderate volatility, allowing the detection of odor notes at low percent dilutions in solvents such as dipropylene glycol. The presence of methyl groups influences hydrophobicity and may affect solubility in organic solvents versus aqueous media. The carbomethoxy moiety introduces an ester functional group susceptible to hydrolysis under certain conditions. Thermal stability and reactivity data are limited but the compound is considered chemically stable for storage and analytical purposes. The odor profile emerges as a complex blend of fruity, green, minty, fig-like, and woody notes, maintaining prominence in dilute solutions without strong volatility that could cause rapid evaporation.

None found

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for 1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)octane usage levels up to:
	not for fragrance use.
Recommendation for 1,3,3,5-tetramethyl-8-carbomethoxybicyclo(2.2.2)octane flavor usage levels up to:
	not for flavor use.

Safety references

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