Preferred name | (E)-cinnamaldehyde |
Trivial Name | trans-Cinnamaldehyde |
Short Description | trans-3-phenyl-2-propenal |
Formula | C9 H8 O |
CAS Number | 14371-10-9 |
FEMA Number | 2286 |
FDA UNII | SR60A3XG0F |
Nikkaji Number | J43.393D |
Beilstein Number | 1071571 |
MDL | MFCD00007000 |
Bio Activity Summary | External link |
NMR Predictor | External link |
FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
Synonyms |
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Google Scholar | Start search |
Google Books | Start search |
Google Patents | Start search |
Perfumer & Flavorists | Start search |
EU Patents | Start search |
PubMeb | Start search |
NCBI | Start search |
(E)-3-phenylprop-2-enal | |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 637511 |
Pubchem (sid): | 134990107 |
Flavornet: | 14371-10-9 |
Pherobase: | View |
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
CHEBI: | View |
CHEMBL: | View |
Golm Metabolome Database: | Search |
Metabolomics Database: | Search |
KEGG (GenomeNet): | C00903 |
HMDB (The Human Metabolome Database): | HMDB03441 |
FooDB: | FDB008782 |
Export Tariff Code: | 2912.29.5000 |
Typical G.C. | |
VCF-Online: | VCF Volatile Compounds in Food |
Wikipedia: | View |
Formulations/Preparations: •perfume grade, fcc, 98% min purity. •chief ingredient (up to 90%) of oil of cinnamon. •cinnacure a3005; active ingredient 30.00% cinnamaldehyde •cinnacure ready to use; active ingredient 0.255% cinnamaldehyde |
Alfa Biotechnology | BOC Sciences |
Coompo | ExtraSynthese |
Santa Cruz Biotechnology | Sigma-Aldrich |
TCI AMERICA |
Material listed in food chemical codex | No |
Molecular weight | 132.16195678711 |
Specific gravity | @ 20 °C |
Pounds per Gallon | 8.756 to 8.797 |
Refractive Index | 1.619 to 1.625 @ 20 °C |
Vapor Pressure | 0.027 mmHg @ 25 °C |
Flash Point TCC Value | 71.11 °C TCC |
logP (o/w) | 1.82 |
Solubility | |
alcohol | Yes |
water, 2150 mg/L @ 25 °C (est) | Yes |
water | No |
Odor Type: Spicy | |
sweet, spicy, candy, cinnamon, warm | |
General comment | At 10.00 % in dipropylene glycol. sweet spice candy cinnamon red hots warm |
Flavor Type: Spicy | |
cinnamon, spicy | |
General comment | Cinnamon spicy |
(data available) |
Applications | |
Odor purposes | Allspice, Almond, Apricot, Balsam, Banana, Bubble gum, Butterscotch, Carnation, Cassia, Cherry, Chypre, Cinnamon, Cranberry, Date, Floral, Florida soap, Foliage, Herbal, Hyacinth, Millefleurs, Mint, Myrrh, Oriental, Patchouli, Plum, Potpourri, Raspberry, Rose, Sassafras, Spice, Strawberry, Tonka bean, Tuberose, Valerian, Vanilla, Windsor soap |
Flavoring purposes | Catsup, Cherry wild cherry, Chocolate cacao, Cola, Grenadine, Sesame, Valerian |
Other purposes | Aramis, Brut, Canoe, Cinnabar, Halston, L'air du temps, L'origan, Norell, Old spice, Opium, Paco rabanne, Pierre cardin, Sensen, Youth dew |
Preferred SDS: View | |
European information : | |
Most important hazard(s): | |
Xn - Harmful. | |
R 21/41 - Harmful in contact with skin, risk of serious damage to eyes. R 38 - Irritating to skin. R 43 - May cause sensitisation by skin contact. S 02 - Keep out of the reach of children. S 24 - Avoid contact with skin. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. | |
Hazards identification | |
Classification of the substance or mixture | |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
None found. | |
GHS Label elements, including precautionary statements | |
Pictogram | |
Hazard statement(s) | |
None found. | |
Precautionary statement(s) | |
None found. | |
Oral/Parenteral Toxicity: | |
Not determined | |
Dermal Toxicity: | |
Not determined | |
Inhalation Toxicity: | |
Not determined |
Category: | |||
flavor and fragrance agents | |||
RIFM Fragrance Material Safety Assessment: Search | |||
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
IFRA Critical Effect: | |||
Sensitization | |||
IFRA fragrance material specification: | |||
The concentration of Cinnamic aldehyde in the finished cosmetic product should not exceed 0.1%. | |||
View IFRA Standards Library for complete information. | |||
Please review Amendment 49 IFRA documentation for complete information. | |||
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): | |||
Category 1: Products applied to the lips | |||
0.02 % | |||
Category 2: Products applied to the axillae | |||
0.02 % | |||
Category 3: Products applied to the face/body using fingertips | |||
0.05 % | |||
Category 4: Products related to fine fragrance | |||
0.05 % | |||
Category 5: Products applied to the face and body using the hands (palms), primarily leave-on | |||
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on | |||
0.05 % | |||
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on | |||
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on | |||
Category 5D: Baby Creams, baby Oils and baby talc | |||
Category 6: Products with oral and lip exposure | |||
0.40 % | |||
Category 7: Products applied to the hair with some hand contact | |||
Category 7A: Rinse-off products applied to the hair with some hand contact | |||
0.40 % | |||
Category 7B: Leave-on products applied to the hair with some hand contact | |||
Category 8: Products with significant anogenital exposure | |||
0.05 % | |||
Category 9: Products with body and hand exposure, primarily rinse off | |||
0.05 % | |||
Category 10: Household care products with mostly hand contact | |||
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) | |||
0.05 % | |||
Category 10B: Household aerosol/spray products | |||
Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate | |||
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure | |||
See Note % | |||
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure | |||
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin | |||
Notes: | |||
IFRA FLAVOR REQUIREMENTS: | |||
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. | |||
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again. | |||
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org). | |||
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product. | |||
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
publication number: 3 | |||
Click here to view publication 3 | |||
average usual ppm | average maximum ppm | ||
baked goods: | - | 180.00000 | |
beverages(nonalcoholic): | - | 9.00000 | |
beverages(alcoholic): | - | - | |
breakfast cereal: | - | - | |
cheese: | - | - | |
chewing gum: | - | 4900.00000 | |
condiments / relishes: | - | 20.00000 | |
confectionery froastings: | - | - | |
egg products: | - | - | |
fats / oils: | - | - | |
fish products: | - | - | |
frozen dairy: | - | 7.70000 | |
fruit ices: | - | 7.70000 | |
gelatins / puddings: | - | - | |
granulated sugar: | - | - | |
gravies: | - | - | |
hard candy: | - | 700.00000 | |
imitation dairy: | - | - | |
instant coffee / tea: | - | - | |
jams / jellies: | - | - | |
meat products: | - | 60.00000 | |
milk products: | - | - | |
nut products: | - | - | |
other grains: | - | - | |
poultry: | - | - | |
processed fruits: | - | - | |
processed vegetables: | - | - | |
reconstituted vegetables: | - | - | |
seasonings / flavors: | - | - | |
snack foods: | - | - | |
soft candy: | - | - | |
soups: | - | - | |
sugar substitutes: | - | - | |
sweet sauces: | - | - |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 214: alpha,beta-Unsaturated aldehydes and precursors from chemical subgroup 3.1 of FGE.19: Cinnamyl derivatives[1] View page or View pdf |
EPI System: View |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
Carcinogenic Potency Database:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :637511 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:1 |
(E)-3-phenylprop-2-enal |
Chemidplus:0014371109 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:GD6476000 for cas# 14371-10-9 |