1-(2-hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one

General Material Information

Preferred name	1-(2-hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one
Trivial Name	1-(2-hydroxy-4-methoxyphenyl)-3-(2-pyridyl)propan-1-one
Formula	C15 H15 N O3
CAS Number	1190229-37-8
FEMA Number	4723
FDA UNII	EJ17MZ1LNZ
xLogP3-AA	2.60 (est)
NMR Predictor	External link
JECFA Food Flavoring	2160 1-(2-hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	1190229-37-8 ; 1-(2-HYDROXY-4-METHOXYPHENYL)-3-(PYRIDIN-2-YL)PROPAN-1-ONE
Synonyms	1-(2-hydroxy-4-methoxyphenyl)-3-(2-pyridyl)propan-1-one 1-propanone, 1-(2-hydroxy-4-methoxyphenyl)-3-(2-pyridinyl)-

	1-(2-hydroxy-4-methoxyphenyl)-3-(2-pyridyl)propan-1-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	49869549
Pubchem (sid):	342527123

Publications by WIPO Patents
PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR
Publications by Leffingwell & Associates
Flavor Properties of FEMA GRAS List 25 flavor chemicals

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	Search
FDA Listing of Food Additive Status:	View
ChemSpider:	View

Material listed in food chemical codex	No
Molecular weight	257.28915405273
Melting Point	65 to 66°C @ 760 mm Hg
Boiling Point	456 to 457°C @ 760 mm Hg
Flash Point TCC Value	230.1 °C TCC
logP (o/w)	2.833 est
Solubility
alcohol	Yes
water, 3969 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Savory
General comment	Sweet savory
Flavor Type: Salty
umami, sweet, salty, savory
General comment	At 2.00 ppm in 0.3% salt solution. umami sweet salty savory


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavoring agents
Recommendation for 1-(2-hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 25
Click here to view publication 25
		average usual ppm	average maximum ppm
baked goods:		2.00000	25.00000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		5.00000	25.00000
chewing gum:		-	-
condiments / relishes:		2.00000	25.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		2.00000	2.00000
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		5.00000	25.00000
hard candy:		-	-
imitation dairy:		5.00000	25.00000
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		5.00000	25.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		5.00000	5.00000
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		5.00000	50.00000
snack foods:		5.00000	25.00000
soft candy:		-	-
soups:		-	-
sugar substitutes:		5.00000	25.00000
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

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EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :49869549

National Institute of Allergy and Infectious Diseases:Data

1-(2-hydroxy-4-methoxyphenyl)-3-(2-pyridyl)propan-1-one

Chemidplus:1190229378