We have found
46588
results matching your criteria.
Please wait while we search...
hydrocortisone
General Material Information
| Preferred name | hydrocortisone |
| Trivial Name | Cortisol |
| Short Description | 17-hydroxycorticosterone |
| Formula | C21 H30 O5 |
| CAS Number | 50-23-7 |
| Deleted CAS Number | 8056-08-4 |
| ECHA Number | 200-020-1 |
| FDA UNII | WI4X0X7BPJ |
| Nikkaji Number | J1.908I |
| MDL | MFCD00011654 |
| Bio Activity Summary | External link |
| NMR Predictor | External link |
| Synonyms |
|
US / EU / FDA / JECFA / FEMA / Scholar / Patents
| Google Scholar | Start search |
| Google Books | Start search |
| Google Patents | Start search |
| Perfumer & Flavorists | Start search |
| EU Patents | Start search |
| PubMeb | Start search |
| NCBI | Start search |
Other Information
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C00735 |
| HMDB (The Human Metabolome Database): | HMDB00063 |
| FooDB: | FDB021888 |
| Export Tariff Code: | 2937.21.0020 |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •ointment: 0.5% cortizone-5, (pfizer), 1% cortizone-10, (pfizer), hydroskin, (rugby), 2.5% hytone, (dermik). pledgets (saturated with solution): 0.5% massengill medicated soft cloth towelette (with parabens and propylene glycol), (glaxosmithkline). solution: 1% cortaid faststick maximum strength (with alcohol and methylparaben), (pfizer), cortaid spray maximum strength (with alcohol and methylparaben), (pfizer), cortizone-10 scalp itch formula liquid (with alcohol sd 40-2 60% vv, benzyl alcohol, and propylene glycol), (pfizer), penecort (with alcohol sd 40-2 57%, benzyl alcohol, and propylene glycol), (allergan), texacort (with sd alcohol 33% and propylene glycol), (sirius), 2.5% texacort, (sirius). •lotion: 0.5% hydroskin, (rugby). 1% ala-cort, (del-ray), aquanil hc (with benzyl alcohol), (person & covey), cetacort (with parabens), (healthpoint), dermacort (with benzyl alcohol), (solvay) hydroskin, (rugby) lacticare-hc, (stiefel) nutracort (with parabens), (healthpoint), sarnol hc, (stiefel), 2% ala-scalpt, (del-ray); 2.5% hydrocortisone lotion, (glades), hydrocortisone lotion, (major), hytone (with propylene glycol), (dermik), lacticare-hc, (stiefel), nutracort (with parabens), (healthpoint), proctocream-hc (with benzyl alcohol), (physicians total care). •topical: cream: 0.5% cortizone-5 (with aloe and parabens), (pfizer), cortizone for kids ( with aloe and parabens), (pfizer); 1% ala-cort, (del-ray), cortaid intensive therapy (with parabens and propylene glycol), (pfizer), cortizone-10 (with aloe and parabens), (pfizer), cortizone-10 external anal itch relief creme ( with aloe and parabens), (pfizer), dermacort, (solvay), dermicort (republic), hydroskin, (rugby), hytone (with propylene glycol), (dermik), penecort (with benzyl alcohol and propylene glycol), (allergan), preparation h hydrocortisone (with parabens and propylene glycol), (wyeth); 2.5% anusol-hc (with benzyl alcohol and propylene glycol), (pfizer), hytone (with propylene glycol), (dermik). gel: 1% cortagel extra strength, (norstar). •rectal: cream: 1 proctocort ( with benzyl alcohol and propylene glycol), (monarch); suspension: 100 mg60 ml cortenema ( with methylparaben), (solvay), hydrocortisone enema, (copley). •powder: (available by nonproprietary name). rectal: aerosol, foam suspension: 10% cortifoam (with parabens, propylene glycol, and chlorofluorohydrocarbon propellants), (schwarz). suppositories: 25 mg anucort-hc, (g&w), anu-med hc, (major), anusol-hc, (pfizer). hemorrhoidal-hc, (alpharma), hemorrhoidal-hc, (cmc), hemorrhoidal-hc, (sandoz), hemorrhoidal-hc, (rugby), hemorrhoidal-hc, (udl), hemril-hc uniserts, (upsher-smith), hydrocortisone acetate suppositories, (paddock), hydrocortisone acetate suppositories, (teva), hydrocortisone acetate suppositories, (udl), hydrocortisone acetate suppositories, (united research), 30 mg proctocort, (monarch). hydrocortisone acetate •powder: oral: tablets: 5 mg cortef (scored), (pfizer); 10 mg cortef (scored), (pfizer), hydrocortone (scored), (merck); 20 mg cortef (scored), (pfizer). •topical: cream: 0.5% corticaine (with parabens), (ucb); 0.5% (of hydrocortisone) cortaid sensitive skin formula (with aloe and parabens), (pfizer); 1% (of hydrocortisone) caldecort anti-itch (with propylene glycol), (novartis), cortaid maximum strength (with aloe and methylparaben), (pfizer), dermarest dricort, del dermtex hc (with menthol 1%), (pfeiffer), nupercainal hydrocortisone anti-itch cream (with propylene glycol), (novartis). lotion: 0.5% (of hydrocortisone) (available by nonproprietary name) ointment: 0.5% (of hydrocortisone) cortaid sensitive skin formula (with aloe and parabens), (pfizer); 1% anusert hc-1, (g&w). gynecort 10, (combe), lanacort 10, (combe); 1% (of hydrocortisone) anusol-hc-1, (pfizer), cortaid maximum strength (with aloe and methylparaben), (pfizer). paste: 0.5% orabase (hca), colgate solution 1% scalp-aid, (major), scalpcort maximum strength, clay-park 1% (of hydrocortisone) dermtex hc spray, (pfeiffer). hydrocortisone acetate •topical: cream: 0.1% pandel (with parabens and propylene glycol), (savage) hydrocortisone buteprate •topical: cream: 0.1% locoid (with methylparaben), (ferndale). ointment: 0.1% locoid, (ferndale). solution: 0.1% locoid (with isopropyl alcohol 50% and povidone), (ferndale). hydrocortisone butyrate •topical: cream: 0.2% westcort (with propylene glycol), (westwood-squibb). ointment: 0.2% westcort (with propylene glycol), (westwood-squibb). •parenteral: for injection: 100 mg (of hydrocortisone) a-hydrocort (with benzyl alcohol 18 mg in univial), (hospira), solu-cortef (preservative-free in vials or with benzyl alcohol 18 mg in act-o-vial), (pfizer); 250 mg (of hydrocortisone) a-hydrocort ( with benzyl alcohol 18 mg in univial), (hospira), solu-cortef (with benzyl alcohol 16.4 mg in act-o-vial), (pfizer); 500 mg (of hydrocortisone) a-hydrocort (with benzyl alcohol 36 mg in univial), (hospira), solu-cortef (with benzyl alcohol 33.4 mg in act-o-vial), (pfizer), 1 g (of hydrocortisone) a-hydrocort ( with benzyl alcohol 72 mg in univial), (hospira), solu-cortef ( with benzyl alcohol 66.9 mg in act-o-vial), (pfizer). hydrocortisone sodium succinate •parenteral: injection: 50 mg (of hydrocortisone) per ml hydrocortone phosphate (with parabens and sodium bisulfite), (merck). hydrocortisone sodium phosphate •powder: parenteral: injectable suspension: 25 mgml, 50 mgml hydrocortone acetate (with benzyl alcohol), (merck). hydrocortisone acetate •grade: usp. also used as acetate and sodium succinate salts. | |
Suppliers
PhysChem Properties
| Material listed in food chemical codex | No |
| Molecular weight | 362.4660949707 |
| Vapor Pressure | 1.35 mmHg @ 25 °C |
| Flash Point TCC Value | 310.4 °C TCC |
| logP (o/w) | 1.61 |
| Solubility | |
| water, 320 mg/L @ 25 °C (exp) | Yes |
| water, 219.6 mg/L @ 25 °C (est) | Yes |
Safety Information
Safety information
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-man TDLo 400 mg/kg/10D- BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS Psychopharmacology Vol. 145, Pg. 260, 1999. intraperitoneal-rat LD50 150 mg/kg Japanese Journal of Pharmacology. Vol. 21, Pg. 377, 1971. | |
| Dermal Toxicity: | |
| subcutaneous-mouse LD50 > 500 mg/kg Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 24(3), Pg. 26, 1990. subcutaneous-rat LD50 449 mg/kg Toxicology and Applied Pharmacology. Vol. 8, Pg. 250, 1966. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in use information
| Category: | |||
| pharmaceuticals / chemical synthisis | |||
| Recommendation for hydrocortisone usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for hydrocortisone flavor usage levels up to: | |||
| not for flavor use. | |||
Safety references
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA Substance Registry Services (TSCA):50-23-7 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :5754 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| Chemidplus:0000050237 |
| RTECS:GM8925000 for cas# 50-23-7 |