(E)-3-methyl-5-cyclotetradecen-1-one

General Material Information

Preferred name	(E)-3-methyl-5-cyclotetradecen-1-one
Trivial Name	(5E)-3-Methyl-5-cyclotetradecen-1-one
Short Description	cosmone (Givaudan)
Formula	C15 H26 O
CAS Number	259854-70-1
FDA UNII	Search
Nikkaji Number	J3.363.257F
xLogP3-AA	4.90 (est)
NMR Predictor	External link
Synonyms	cosmone (Givaudan) 5-cyclotetradecen-1-one, 3-methyl-, (5E)- (E)-3-methyl cyclotetradec-5-en-1-one (5E)-3-methylcyclotetradec-5-en-1-one (E)-3-methylcyclotetradec-5-en-1-one 5-Cyclotetradecen-1-one, 3-methyl-, (5E)- (5E)-3-Methyl-5-cyclotetradecen-1-one (E)-3-Methylcyclotetradec-5-en-1-one trans-Cosmone (E)-Cosmone Cosmone

	(5E)-3-methylcyclotetradec-5-en-1-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	66823518
Pubchem (sid):	135319439

Publications by US Patents
6,326,349 - Methylcyclotetradec-5-en-1-ones

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Givaudan	Indukern F&F
Lluch Essence	Pell Wall Perfumes
The Perfumers Apprentice	Vigon International
Indukern, S.A. F&F Ingredients Division	Lluch Essence S.L.

Material listed in food chemical codex	No
Molecular weight	222.37141418457
Boiling Point	328 to 329°C @ 760 mm Hg
Vapor Pressure	0.00018 mmHg @ 25 °C
Flash Point TCC Value	137.22 °C TCC
logP (o/w)	5.345 est
Solubility
water, 1.083 mg/L @ 25 °C (est)	Yes

Odor Type: Musk
musk, animal, powdery, fatty, cloth laundered cloth, ambergris, anisic, woody
Luebke, William tgsc, (2017)	At 10.00 % in dipropylene glycol. musk animal powdery fatty laundered cloth ambergris anisic woody
An intensely rich, powerful and elegant musk. The warm powdery facets of Cosmone are reminiscent of classic nitromusks with a subtle ambregris nuance. A trace of Cosmone brings an outstanding cosmetic volume to all types of accords. While extremely effective by itself, Cosmone also offers excellent synergy with other ingredients.	Musky, Warm, Powdery
This a strong, highly effective musk even in small doses, smooth, cosmetic, full and with a slightly powdery dry-down and nitro-musk-like effects comparable with that found in Velvione. It has exceptionally high impact and warmth and some people also detect an anisic as well as an ambergris aspect in this material.	Musk, sweet, warm, rich, powdery, ambergris, animalic. Powerful


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 5), H303 Acute toxicity, dermal (Category 5), H313
GHS Label elements, including precautionary statements

Pictogram

Signal word	Danger
Hazard statement(s)
H303 - May be harmfulif swallowed H313 - May be harmful in contact with skin
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P272 - Contaminated work clothing should not be allowed out of the workplace. P273 - Avoid release to the environment. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302 + P352 - IF ON SKIN: wash with plenty of soap and water. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P361 - Remove/Take off immediately all contaminated clothing. P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for (E)-3-methyl-5-cyclotetradecen-1-one usage levels up to:
	5.0000 % in the fragrance concentrate.

Recommendation for (E)-3-methyl-5-cyclotetradecen-1-one flavor usage levels up to:
	not for flavor use.

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):259854-70-1

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :66823518

National Institute of Allergy and Infectious Diseases:Data

(5E)-3-methylcyclotetradec-5-en-1-one

Chemidplus:0259854701