dihydro-alpha-terpinyl acetate

Dihydro-alpha-terpinyl acetate is a synthetic organic ester with the molecular formula C₁₂H₂₂O₂, classified under fragrance compounds. It appears as a liquid with a medium-strength woody odor, complemented by fresh herbal and lime cologne notes. Known by various synonyms such as acetic acid p-menthan-8-ol ester and alpha,alpha-dihydroterpinyl acetate, it is documented in chemical databases like PubChem. The compound is typically derived through esterification of dihydroterpineol with acetic acid. Its sensory profile and physicochemical stability make it suitable for incorporation in diverse fragrance formulations.

Dihydro-alpha-terpinyl acetate does not occur naturally in significant amounts but is valued in the fragrance industry for imparting woody, cedar, pine, cologne, and herbal notes. It is a common ingredient in perfuming agents designed for soaps, shampoos, detergents, and lotions. Its inclusion enhances the longevity and substantivity of woody accords, improving scent persistence over time. The International Fragrance Association (IFRA) (Global) provides guidelines limiting its concentration in fragrance concentrates to ensure safe consumer use, reflecting its recognized applications and regulatory oversight.

This ester exhibits a moderate molecular weight near 198.3 g/mol and presents a boiling point range between 222 and 223 degrees Celsius at standard pressure. Its specific gravity ranges from 0.93 to 0.938 at 25 °C, and refractive indices vary from 1.447 to 1.451 at 20 °C. The compound has an estimated log P value around 4.06, indicating relatively high lipophilicity, which influences its solubility and interaction in formulations. Its vapor pressure at 25 °C is low, approximately 0.103 mmHg, contributing to its moderate volatility and sustained scent release. The flash point is about 100 °C (212 °F), requiring careful handling during manufacturing. Dihydro-alpha-terpinyl acetate dissolves well in alcohols but shows limited water solubility, which affects its dispersion in aqueous preparations. Overall, these physico-chemical attributes support its functional role in fragrance blends.

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Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 875, 1974.
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for dihydro-alpha-terpinyl acetate usage levels up to:
	10.0000 % in the fragrance concentrate.
Recommendation for dihydro-alpha-terpinyl acetate flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

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Toxicology Citations:Search

EPA Substance Registry Services (TSCA):80-25-1

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6631

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

2-(4-methylcyclohexyl)propan-2-yl acetate

Chemidplus:0000080251