We have found
46590
results matching your criteria.
Please wait while we search...
(+)-2-ethyl fenchol
(+)-2-ethyl fenchol is a bicyclic terpene alcohol featuring an earthy aroma, utilized mainly in fragrances with molecular formula C12H22O.
General Material Description
(+)-2-ethyl fenchol is a bicyclic terpene alcohol recognized for its distinct earthy odor characteristic. This compound's molecular formula is C12H22O, and it is structurally defined as (1R,2R,4S)-2-ethyl-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol. It appears as a colorless liquid under standard conditions and is known chemically both by its trivial name and several systematic synonyms. The earthy olfactory note it provides is typical at concentrations such as 0.10% in dipropylene glycol, imparting a humus-like scent. Its chemical identity and properties are indexed under databases like PubChem CID 44148734. The compound is primarily sourced through synthetic organic chemistry routes for use in fragrance applications.
Occurrence, Applicability & Potential Uses
(+)-2-ethyl fenchol occurs naturally as a derivative of bicyclic terpene alcohols, though it is typically produced synthetically for commercial use. Its primary application is as a fragrance agent, valued for contributing an earthy, natural note within complex scent formulations. While it does not have documented food flavoring uses, its olfactory characteristics suit perfumery and scented consumer products. Its usage and safety are monitored under standards such as IFRA (Global), to ensure acceptable exposure levels in fragrance compositions. The compound contributes to enhancing aroma complexity particularly in woody, earthy-themed fragrances.
Physico-Chemical Properties Summary
(+)-2-ethyl fenchol exhibits physicochemical properties that influence its formulation behavior and olfactory delivery. It has a boiling point ranging between 224 and 225°C at 760 mm Hg, indicating moderate volatility. The vapor pressure at 25°C is low, approximately 0.018 mmHg, suggesting a slow evaporation rate in ambient conditions. Its estimated log P value of about 3.779 reflects moderate lipophilicity, affecting solubility and skin absorption characteristics. The compound’s water solubility is modest, estimated at 99.48 mg/L at 25°C, supporting miscibility considerations in polar solvents. The flash point measured at 192°F (approximately 89°C) indicates standard flammability precautions during handling. These combined properties make it suitable for formulation in fragrance bases requiring sustained release and stability.
FAQ
What is (+)-2-ethyl fenchol and what are its characteristic properties?
(+)-2-ethyl fenchol is a bicyclic terpene alcohol with the molecular formula C12H22O. It is known for an earthy odor reminiscent of humus when diluted in suitable solvents. Its chemical structure includes three methyl groups and an ethyl substituent on a bicyclo[2.2.1]heptane framework bearing a hydroxyl group. The compound is a colorless liquid under standard conditions and features a boiling point near 224 to 225°C. It exhibits moderate volatility and lipophilicity, making it primarily valuable as a fragrance ingredient.
How is (+)-2-ethyl fenchol typically used and where does it occur?
(+)-2-ethyl fenchol is mainly utilized as a fragrance agent in perfumery and related scented consumer products. While it can be found as a natural derivative of some terpene sources, commercial supplies are generally synthetic for consistency and purity. The compound imparts an earthy and natural note, enhancing the olfactory complexity of woody or green fragrance styles. Its usage levels and exposure are managed according to IFRA (Global) standards to ensure proper safety in applications.
What safety assessments and regulations relate to (+)-2-ethyl fenchol?
(+)-2-ethyl fenchol does not carry classification under OSHA’s Globally Harmonized System (29 CFR 1910) for hazards and shows no defined precautionary statements. The compound is reviewed by the Research Institute for Fragrance Materials (RIFM) and included in IFRA’s Code of Practice (Global), which recommends usage restrictions particularly advising against flavor use. Comprehensive data on toxicity are not determined, and standard chemical safety summaries can be found through regulatory and scientific databases such as EPA TSCA, PubChem, and ChemIDplus.
US / EU / FDA / JECFA / FEMA / Scholar / Patents
| Google Scholar | Start search |
| Google Books | Start search |
| Google Patents | Start search |
| Perfumer & Flavorists | Start search |
| EU Patents | Start search |
| PubMeb | Start search |
| NCBI | Start search |
Other Information
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
General Material Information
| Preferred name | (+)-2-ethyl fenchol |
| Trivial Name | (1R,2R,4S)-2-Ethyl-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol |
| Short Description | bicyclo[2.2.1]heptan-2-ol, 2-ethyl-1,3,3-trimethyl-, (1R,2R,4S)- |
| Formula | C12 H22 O |
| CAS Number | 137255-07-3 |
| FDA UNII | Search |
| Beilstein Number | 3044187 |
| xLogP3-AA | 2.90 (est) |
| NMR Predictor | External link |
| Synonyms |
|
Suppliers
| Parchem |
PhysChem Properties
| Material listed in food chemical codex | No |
| Molecular weight | 182.30653381348 |
| Boiling Point | 224 to 225°C @ 760 mm Hg |
| Vapor Pressure | 0.018 mmHg @ 25 °C |
| Flash Point TCC Value | 88.9 °C TCC |
| logP (o/w) | 3.779 est |
| Solubility | |
| water, 99.48 mg/L @ 25 °C (est) | Yes |
Organoleptic Properties
| Odor Type: Earthy | |
| earthy, humus | |
| General comment | At 0.10 % in dipropylene glycol. earthy humus |
Safety Information
Safety information
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in use information
| Category: | |||
| fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for (+)-2-ethyl fenchol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety references
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):137255-07-3 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :44148734 |
| National Institute of Allergy and Infectious Diseases:Data |
| (1R,2R,4S)-2-ethyl-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol |
| Chemidplus:0137255073 |