citronellyl (R)-lactate

Citronellyl (R)-lactate is an organic ester characterized by the molecular formula C₁₃H₂₄O₃. It is a colorless to pale liquid typically recognized for its floral odor resembling lily of the valley, combined with a warm and rich natural note. This compound is identified by its systematic name 3,7-dimethyl-6-octen-1-yl (2R)-2-hydroxypropanoate and is known by several synonyms including rosilial plus. Citronellyl (R)-lactate is primarily sourced through synthetic esterification processes involving citronellol derivatives and lactic acid. It is indexed in chemical registries such as PubChem with CID 57375717, providing comprehensive structural and physicochemical data. Due to its olfactory qualities, it is valued in fragrance synthesis and related applications.

Although citronellyl (R)-lactate may not be a naturally occurring metabolite, it derives structurally from compounds found in natural essential oils, notably citronellol. Its main applications lie in perfumery and fragrance formulations where it imparts a distinct floral character. The compound’s suitability for fragrance use is governed by standards including IFRA (Global), which provides guidelines on concentration limits and safe application. Citronellyl (R)-lactate is predominantly used as a fragrance agent in fine fragrances, personal care products, and household scent formulations. It should be noted that it is not intended for flavor use according to current regulatory recommendations.

Citronellyl (R)-lactate presents moderate volatility and a relatively high flash point measured at 256 °F, contributing to its stability in fragrance formulations. Its estimated log P value of approximately 3.4 indicates moderate lipophilicity, favoring solubility in organic solvents such as alcohols while exhibiting limited water solubility measured near 100 mg/L at 25 °C. These properties influence its diffusion and evaporation behavior in ambient environments. The compound exists as a chiral ester, which can affect its sensory profile and interaction with olfactory receptors. Its physical state as a liquid at room temperature and appreciable stability make it compatible with various topical and air dispersion products.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
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(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
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Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for citronellyl (R)-lactate flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

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Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :57375717

National Institute of Allergy and Infectious Diseases:Data

3,7-dimethyloct-6-enyl (2R)-2-hydroxypropanoate