2-isobutyl-3,5-(and 3,6)-dimethyl pyrazine

General Material Information

Trivial Name	2-isobutyl-3,5-(and 3,6)-dimethyl pyrazine
Short Description	3,5- and 3,6-dimethyl-2-isobutylpyrazine
Formula	C10 H16 N2
CAS Number	38888-81-2
FEMA Number	4100
FDA UNII	Search
JECFA Food Flavoring	2130 3,5- and 3,6-dimethyl-2-isobutylpyrazine
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	3,5- AND 3,6-DIMETHYL-2-ISOBUTYLPYRAZINE
Synonyms	2-iso butyl-3,(5 and 6)-dimethylpyrazine 2-iso butyl-3,5-(and 3,6)-dimethylpyrazine 3,5-and 3,6-dimethyl-2-isobutyl pyrazine 3,5-and 3,6-dimethyl-2-isobutylpyrazine 3,5,6-dimethyl-2-isobutylpyrazine 3,5-and 3,6-dimethyl-3-(2-methyl propyl) pyrazine 3,5-and 3,6-dimethyl-3-(2-methyl propyl)-1,4-diazine

HMDB (The Human Metabolome Database):	Search
FooDB:	FDB009317
VCF-Online:	VCF Volatile Compounds in Food

Aston Chemical	BOC Sciences
Jiangyin Healthway	Penta International
Synerzine	Jiangyin Healthway International Trade Co., Ltd
Penta International Corporation

Material listed in food chemical codex	No
Molecular weight	164.25152587891
Specific gravity	@ 25 °C
Pounds per Gallon	7.689 to 7.772
Refractive Index	1.489 to 1.494 @ 20 °C
Boiling Point	73 to 75°C @ 2 mm Hg
Solubility
alcohol	Yes
water	No

Odor Type: Cocoa
cocoa, hazelnut, musty, earthy, roasted, nutty
General comment	At 0.10 % in dipropylene glycol. cocoa hazelnut musty earthy roasted nutty

Applications	flavor and fragrance agents
Odor purposes	Balsam , Fern , Floral , Moss , Oriental
Flavoring purposes	Chocolate cocoa , Nut


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-isobutyl-3,5-(and 3,6)-dimethyl pyrazine usage levels up to:
	0.3000 % in the fragrance concentrate.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
Click here to view publication 22
		average usual ppm	average maximum ppm
baked goods:		1.50000	2.00000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		1.50000	2.00000
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		2.00000	3.00000
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		0.50000	1.50000
reconstituted vegetables:		-	-
seasonings / flavors:		5.00000	10.00000
snack foods:		-	-
soft candy:		-	-
soups:		0.50000	1.50000
sugar substitutes:		-	-
sweet sauces:		2.00000	3.00000

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

Chemidplus:0038888812