2,5-dithiahexane

General Material Information

Preferred name	2,5-dithiahexane
Trivial Name	1,2-Bis(methylthio)ethane
Short Description	ethane, 1,2-bis(methylthio)-
Formula	C4 H10 S2
CAS Number	6628-18-8
FEMA Number	4298
FDA UNII	D37463NMIR
Nikkaji Number	J101.104I
xLogP3-AA	1.50 (est)
Bio Activity Summary	External link
NMR Predictor	External link
JECFA Food Flavoring	1707 2,5-dithiahexane
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	6628-18-8 ; 2,5-DITHIAHEXANE
Synonyms	ethane, 1,2-bis(methylthio)- 1,2-bis( methyl mercapto) ethane 1,2-bis( methyl thio) ethane 1,2-bis( methylsulfanyl)ethane 1,2-bis( methylthio)ethane 1,2-bis(methylsulfanyl)ethane 1,2-Bis(methylthio)ethane 1,2-Bis(methylmercapto)ethane NSC 60544

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	HMDB31708
FooDB:	FDB008371
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Material listed in food chemical codex	No
Molecular weight	122.25370025635
Specific gravity	@ 25 °C
Pounds per Gallon	8.646 to 8.729
Refractive Index	1.526 to 1.533 @ 20 °C
Boiling Point	178 to 180°C @ 760 mm Hg
Vapor Pressure	1.428 mmHg @ 25 °C
Flash Point TCC Value	59.44 °C TCC
logP (o/w)	1.538 est
Solubility
alcohol	Yes
water, 5188 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Sulfurous
sulfurous, dairy
General comment	At 0.10 % in propylene glycol. sulfurous dairy

Applications	flavoring agents
Flavoring purposes	Butter, Cream, Cream ice cream, Cream sour cream, Custard, Dairy, Milk, Milk buttermilk, Milk malted milk, Yogurt


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavoring agents
Recommendation for 2,5-dithiahexane usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 23
Click here to view publication 23
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		0.02000	0.20000
confectionery froastings:		-	-
egg products:		0.02000	0.20000
fats / oils:		-	-
fish products:		0.02000	0.20000
frozen dairy:		0.02000	0.10000
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		0.02000	0.20000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		0.02000	0.20000
milk products:		0.01000	0.10000
nut products:		0.01000	0.10000
other grains:		-	-
poultry:		0.02000	0.20000
processed fruits:		-	-
processed vegetables:		0.01000	0.10000
reconstituted vegetables:		0.01000	0.10000
seasonings / flavors:		10.00000	50.00000
snack foods:		0.02000	0.10000
soft candy:		-	-
soups:		0.02000	0.10000
sugar substitutes:		-	-
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :23110

National Institute of Allergy and Infectious Diseases:Data

1,2-bis(methylsulfanyl)ethane

Chemidplus:0006628188