menthyl pyrrolidone carboxylate

General Material Information

Preferred name	menthyl pyrrolidone carboxylate
Trivial Name	(5-methyl-2-propan-2-ylcyclohexyl) 5-oxopyrrolidine-2-carboxylate
Formula	C15 H25 N O3
CAS Number	68127-22-0
CAS Number	64519-44-4
Deleted CAS Number	52528-10-6
FEMA Number	4155
ECHA Number	268-568-4
FDA UNII	Y27B4585KO
Nikkaji Number	J307.247I
xLogP3-AA	3.00 (est)
NMR Predictor	External link
JECFA Food Flavoring	1858 menthyl pyrrolidone carboxylate
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	52528-10-6 ; MENTHYL PYRROLIDONECARBOXYLATE
Synonyms	(-)- menthyl (+)-2-pyrrolidone-5-carboxylate menthyl PCA (5-methyl-2-propan-2-ylcyclohexyl) 5-oxopyrrolidine-2-carboxylate [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] (2S)-5-oxopyrrolidine-2-carboxylate (1R-(1alpha,2beta,5alpha))-2-iso propyl-5-methyl cyclohexyl 5-oxo-dextro-prolinate (1R-(1alpha,2beta,5alpha))-2-iso propyl-5-methylcyclohexyl 5-oxo-D-prolinate questice (Givaudan)

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
KEGG (GenomeNet):	C03962
HMDB (The Human Metabolome Database):	HMDB32368
FooDB:	FDB009781
ChemSpider:	View

BOC Sciences	Givaudan
Jiangyin Healthway	Parchem
Jiangyin Healthway International Trade Co., Ltd

Material listed in food chemical codex	No
Molecular weight	267.36883544922
Melting Point	68 to 72°C @ 760 mm Hg
Boiling Point	409 to 410°C @ 760 mm Hg
Flash Point TCC Value	201.11 °C TCC
logP (o/w)	3.195 est
Solubility
alcohol	Yes
water, slightly	Yes
water, 14.07 mg/L @ 25 °C (est)	Yes
water	No


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavoring agents
Recommendation for menthyl pyrrolidone carboxylate usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
Click here to view publication 22
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		3000.00000	3000.00000
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		500.00000	500.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):68127-22-0

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :109140

National Institute of Allergy and Infectious Diseases:Data

(5-methyl-2-propan-2-ylcyclohexyl) 5-oxopyrrolidine-2-carboxylate

Chemidplus:0068127220

[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] (2S)-5-oxopyrrolidine-2-carboxylate

Chemidplus:0064519444