plum damascone

Plum damascone, also known as isodamascone (standard), is an organic ketone with the molecular formula C₁₃H₂₀O. It appears as a clear fragrance material notable for its high-intensity floral aroma characterized by plum and rose notes. This compound plays a significant role in perfumery as a fragrance ingredient, imparting complex floral and fruity aspects. Synonyms include 1-(2,4,4-trimethyl-1-cyclohex-2-enyl)but-2-en-1-one and iso damascone. It is a controlled-vocabulary linked chemical entity identified in PubChem. Plum damascone is synthetically derived and primarily used as a fragrance agent in cosmetic and personal care formulations.

Plum damascone does not occur naturally in significant amounts but is a synthetic aroma chemical extensively utilized in the fragrance industry. It is valued for its ability to evoke floral, plum, rose, and tobacco scent nuances, contributing to complexity in perfumes and scented products. According to the International Fragrance Association (IFRA) (Global), its use is regulated to ensure safe exposure levels in consumer formulations. Typical applications include fine fragrances, body care products, and household items where a durable floral plum scent is desired.

Physicochemical attributes of plum damascone influence its formulation and handling in fragrance applications. This ketone exhibits moderate volatility with a boiling point near 266 to 267 °C at atmospheric pressure and a vapor pressure of approximately 0.008 mmHg at 25 °C, indicating low evaporation rate under ambient conditions. Its relative density ranges from 0.918 to 0.926 at 25 °C, and refractive index falls between 1.485 and 1.493 at 20 °C. The compound is soluble in alcohols but has negligible water solubility around 10.31 mg/L at 25 °C, affecting solubilization in aqueous media. The estimated logP value of 3.436 suggests moderate lipophilicity conducive to integration in oil-based systems. Stability is maintained under proper storage, avoiding heat and light, with a shelf life of at least 12 months.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 6300 mg/kg
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Dermal sensitization
	View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.0077 %
Category 2: Products applied to the axillae
0.0023 %
Category 3: Products applied to the face/body using fingertips
0.046 %
Category 4: Products related to fine fragrance
0.043 %
	Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.011 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.011 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.011 %
Category 5D: Baby Creams, baby Oils and baby talc
0.011 %
Category 6: Products with oral and lip exposure
0.025 %
	Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.088 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.088 %
Category 8: Products with significant anogenital exposure
0.0045 %
Category 9: Products with body and hand exposure, primarily rinse off
0.084 %
	Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
0.30 %
Category 10B: Household aerosol/spray products
0.30 %
	Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.17 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.17 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction
	Notes:
IFRA FLAVOR REQUIREMENTS:
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.
use level in formulae for use in cosmetics:
	0.0200 %
Dermal Systemic Exposure in Cosmetic Products:
	0.0005 mg/kg/day (IFRA, 2002)
Recommendation for plum damascone flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

EPA Substance Registry Services (TSCA):70266-48-7

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6438067

National Institute of Allergy and Infectious Diseases:Data

1-(2,4,4-trimethyl-1-cyclohex-2-enyl)but-2-en-1-one

Chemidplus:0033673711