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General Material Information

Preferred name cis-muguet shiseol
Trivial Name cis-p-Menthan-7-ol
Short Description cis-p-menthan-7-ol
Formula C10 H20 O
CAS Number 13828-37-0
FEMA Number 4507
ECHA Number 237-539-8
FDA UNII HOT98SG01O
Nikkaji Number J52.969I
xLogP3-AA 3.00 (est)
NMR Predictor External link
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
Synonyms
  • cyclohexanemethanol, 4-(1-methylethyl)-, cis-
  • cis- dihydro shiseol
  • cis- dihydroshiseol
  • cis- mayol (Firmenich)
  • cis- meijiff (IFF)
  • cis-p- menthan-7-ol
  • cis-para- menthan-7-ol
  • p- menthan-7-ol, cis-
  • cis-4-(1-methylethyl) cyclohexane methanol
  • cis-4-(1-methylethyl)cyclohexanemethanol
  • [cis-4-( propan-2-yl)cyclohexyl]methanol
  • (cis-4-propan-2-ylcyclohexyl)methanol
  • cis-4-iso propyl cyclohexane methanol
  • cis-4-(iso propyl) cyclohexane methanol
  • cis-4-(iso propyl)cyclohexane methanol
  • cis-4-(iso propyl)cyclohexanemethanol
  • cis-4-iso propylcyclohexane methanol
  • (cis-4-iso propylcyclohexyl)methanol
  • cis- tetrahydro perillyl alcohol
  • cis- tetrahydroperillyl alcohol
  • [cis-4-(propan-2-yl)cyclohexyl]methanol
  • p-Menthan-7-ol, cis-
  • cis-4-(1-Methylethyl)cyclohexanemethanol
  • cis-Tetrahydroperillyl alcohol
  • cis-p-Menthan-7-ol
  • (cis-4-Isopropylcyclohexyl)methanol
  • ((1s,4s)-4-Isopropylcyclohexyl)methanol

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

[cis-4-(propan-2-yl)cyclohexyl]methanol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:13828-37-0
Pubchem (cid):83763
Pubchem (sid):135039787
Publications by US Patents
3,993,604 - Alicyclic compounds, their use and process for preparing same
Publications by PubMed
Biotransformation of one monoterpene by sporulated surface cultures of Aspergillus niger and Penicillium sp.
Fragrance Material Review on cis-p-menthan-7-ol.

Other Information

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 156.26860046387
Boiling Point 223 to 224°C @ 760 mm Hg
Vapor Pressure 0.019 mmHg @ 25 °C
Flash Point TCC Value 97.2 °C TCC
logP (o/w) 3.243 est
Solubility
alcohol Yes
water, 258.2 mg/L @ 25 °C (est) Yes
Stability
APC: traces - 0.5% Unspecified
candle: 0.5 - 5% Unspecified
detergent: 0.5 - 5% Unspecified
fine fragrances: 0.5 - 5% Unspecified
shampoo: 0.5 - 5% Unspecified
shower gel: 0.5 - 5% Unspecified
soap: 0.5 - 5% Unspecified
softener: 0.5 - 5% Unspecified

Organoleptic Properties

Odor Type: Floral
fresh, clean, floral, magnolia, muguet, cumin, grassy
Odor strength medium
Substantivity 72 hour(s) at 100.00 %
Luebke, William tgsc, (2017) At 100.00 %. fresh clean floral magnolia hydroxycitronellal cumin grassy
Flavor Type: Floral
floral, fruity, tropical, magnolia, mulberry, melon rind, orange rind, rue
Luebke, William tgsc, (2017) Floral fresh fruity tropical magnolia mango mulberry melon rind orange rind rue

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Dermal sensitization and systemic toxicity
View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.25 %
Category 2: Products applied to the axillae
0.39 %
Category 3: Products applied to the face/body using fingertips
0.099 %
Category 4: Products related to fine fragrance
4.70 %
Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
1.20 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.15 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.20 %
Category 5D: Baby Creams, baby Oils and baby talc
0.049 %
Category 6: Products with oral and lip exposure
0.0099 %
Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.13 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.13 %
Category 8: Products with significant anogenital exposure
0.049 %
Category 9: Products with body and hand exposure, primarily rinse off
0.39 %
Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
0.39 %
Category 10B: Household aerosol/spray products
1.10 %
Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.049 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.049 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
28.00 %
Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 0.500002.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: 1.000005.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 1.000005.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):13828-37-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :83763
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
[cis-4-(propan-2-yl)cyclohexyl]methanol
Chemidplus:0013828370