(E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide

General Material Information

Trivial Name	(E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide
Short Description	rubescenamine
Formula	C20 H21 N O5
CAS Number	125187-30-6
FEMA Number	4773
FDA UNII	NT6KZD17F5
Nikkaji Number	J3.469.403F
NMR Predictor	External link
JECFA Food Flavoring	2227 (E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
Synonyms	(E)-N-[2-( benzo[d][1,3]dioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide (2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide rubescenamine

	(2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	18159637
Pubchem (cas):	125187-30-6

Publications by Google Patents
Cinnamamides as savory flavorings
Publications by PubMed
Rubemamine and Rubescenamine, Two Naturally Occurring N-Cinnamoyl Phenethylamines with Umami-Taste-Modulating Properties.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Material listed in food chemical codex	No
Molecular weight	355.39038085938
Melting Point	153 to 154°C @ 760 mm Hg
Flash Point TCC Value	312.6 °C TCC
logP (o/w)	3.204 est
Solubility
water, 10.77 mg/L @ 25 °C (est)	Yes


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavor enhancers, umami taste enhancer
Recommendation for (E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)prop-2-enamide usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 26
Click here to view publication 26
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		0.20000	2.50000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		2.00000	9.00000
chewing gum:		-	-
condiments / relishes:		2.00000	15.00000
confectionery froastings:		-	-
egg products:		4.00000	15.00000
fats / oils:		2.00000	12.00000
fish products:		2.00000	12.00000
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		2.00000	15.00000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		0.20000	2.50000
jams / jellies:		-	-
meat products:		2.00000	12.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		2.00000	12.00000
processed fruits:		-	-
processed vegetables:		2.00000	12.00000
reconstituted vegetables:		-	-
seasonings / flavors:		10.00000	30.00000
snack foods:		5.00000	30.00000
soft candy:		-	-
soups:		2.00000	15.00000
sugar substitutes:		-	-
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :18159637

National Institute of Allergy and Infectious Diseases:Data

(2E)-N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3,4-dimethoxyphenyl)acrylamide

Chemidplus:0125187306