(4E,9Z)-13-methyloxacyclopentadeca-4,9-dien-2-one

(4E,9Z)-13-methyloxacyclopentadeca-4,9-dien-2-one is a synthetic fragrance compound belonging to the class of macrocyclic lactones. It appears as a clear to slightly yellow liquid possessing a complex aroma described as sweet, aromatic, powdery, musky, floral, and green with jasmin nuances at typical use concentrations such as 10 % in dipropylene glycol. Known also by its synonym (4E,9Z)-13-methyl oxacyclopentadeca-4,9-dien-2-one, it is characterized chemically by a large ring lactone structure containing two double bonds in defined stereochemical configurations. Its PubChem entry provides detailed molecular structure and related chemical data. This compound is typically obtained through chemical synthesis and widely employed within fragrance formulations to impart musk and floral notes.

(4E,9Z)-13-methyloxacyclopentadeca-4,9-dien-2-one does not naturally occur in significant amounts but is synthesized for use in the fragrance industry. Its application includes incorporation into perfumes and scented cosmetic products where it contributes aromatic musky and floral characteristics. Regulatory bodies such as IFRA (International Fragrance Association, Global) provide guidelines for its use, specifying usage limits to ensure safe inclusion in consumer products. Although it is categorized under fragrance agents, it is not approved for flavor use according to IFRA standards. Its role is primarily to enhance olfactory profiles in luxury and everyday scented goods.

This compound's macrocyclic lactone structure imparts characteristic volatility and odor profile desirable in perfumery. The presence of two double bonds in conjugation influences its reactivity and stability under formulation conditions. It typically exhibits moderate solubility in common fragrance solvents like dipropylene glycol. Its clear liquid state contributes to ease of handling and incorporation into various product bases. Absence of significant toxicity classifications facilitates its safe use within recommended concentration limits. The compound's physicochemical parameters such as molecular weight, vapor pressure, and lipophilicity govern its diffusion and perception in fragrance applications.

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for (4E,9Z)-13-methyloxacyclopentadeca-4,9-dien-2-one flavor usage levels up to:
	not for flavor use.

Safety references

None found