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polvolide (Soda)

Polvolide (Soda) is a musk-scented fragrance compound used as a fragrance agent with notable solubility in alcohol and minimal hazard classification.

General Material Description

Polvolide (Soda), also known by its chemical synonym 12-methyl-14-tetradec-9-enolide, is a synthetic musk fragrance compound characterized by a clean, sweet, powdery animalic odor profile when diluted at 1% in dipropylene glycol. It belongs to the lactone class of organic compounds which feature cyclic esters. This compound appears as a colorless ingredient commonly used in fragrance applications. Its molecular structure and properties can be explored through its [PubChem entry](https://pubchem.ncbi.nlm.nih.gov/compound/Polvolide). Polvolide is produced synthetically rather than sourced from natural processes, providing a stable musk note favored in perfumery formulations.

Occurrence, Applicability & Potential Uses

Polvolide occurs only as a manufactured fragrance material rather than being a naturally occurring substance. Its primary use is as a musk-scented fragrance agent within personal care and household products. The compound’s musk character enhances scent complexity and longevity in perfumes and fine fragrances. According to the IFRA (Global) standards, polvolide is recognized within regulatory frameworks applicable to fragrance ingredients, and its usage is guided by relevant safety assessments. Its notable solubility in alcohol facilitates formulation in alcohol-based perfume solutions, although limited water solubility restricts its use in aqueous products.

Physico-Chemical Properties Summary

Polvolide exhibits selective solubility characteristics, being soluble in alcohol solvents but insoluble in water, which influences its dispersion and stability in various formulations. The compound presents a stable lactone structure contributing to its musk odor qualities. These physicochemical traits support its efficient use in perfume concentrates and alcohol-based fragrance blends. Its lack of notable hazard classifications under OSHA HCS implies it does not present significant handling risks under typical usage conditions. The clean and powdery musk odor profile at low concentrations supports its application as a distinctive yet versatile fragrance ingredient.

FAQ

What is polvolide (Soda) and what are its main characteristics?
Polvolide (Soda) is a synthetic fragrance compound known chemically as 12-methyl-14-tetradec-9-enolide. It features a musk odor described as clean, sweet, and powdery with animalic undertones. It belongs to the lactone chemical class and is used primarily as a fragrance agent in perfumery and related products. Polvolide is characterized by its solubility in alcohol and insolubility in water, aiding its incorporation into various alcohol-based fragrance formulations.
Where is polvolide (Soda) typically used and how does it fit into fragrance applications?
Polvolide (Soda) is utilized mainly in fragrance products to impart a musk scent, enhancing the olfactory depth and longevity of perfumes and scented consumer goods. Its physicochemical properties allow it to dissolve efficiently in alcohol solvents, making it appropriate for use in perfume concentrates and other alcohol-based fragrance vehicles. It is not naturally occurring but is synthesized for use in the fragrance industry under established regulatory guidelines such as IFRA (Global).
What are the regulatory and safety considerations associated with polvolide (Soda)?
Polvolide (Soda) is classified without significant hazards under the Globally Harmonized System (GHS) and OSHA Hazard Communication Standard (29 CFR 1910). It does not have established toxicity data for oral, dermal, or inhalation routes and is not approved for flavor uses. Safety assessments by organizations such as RIFM and compliance with IFRA (Global) Code of Practice inform its authorized usage levels. Users should reference these standards and safety documents for appropriate handling and formulation guidelines.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

Leffingwell:Chirality or Article
Pubchem (cas):868846-58-6
Publications by PubMed
Enantioselectivity of the musk odor sensation.

Other Information

HMDB (The Human Metabolome Database):Search
Wikipedia:View

General Material Information

Trivial Name polvolide (Soda)
Short Description 12-methyl-14-tetradec-9-enolide
CAS Number 868846-58-6
FDA UNII Search
Synonyms
  • 12-methyl-14-tetradec-9-enolide

Suppliers

Soda Aromatic

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water No

Organoleptic Properties

Odor Type: Musk
clean, sweet, powdery, animal, musk
General comment At 1.00 % in dipropylene glycol. clean sweet powdery animalic musk

Potential Uses

Applications
Odor purposes Musk

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for polvolide (Soda) flavor usage levels up to:
not for flavor use.

Safety references

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data