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ethanol

Ethanol is a volatile, clear alcohol (C2H6O) with a medium alcoholic odor, used primarily as a solvent and flavor carrier in various applications.
Chemical Structure

General Material Description

Ethanol, also known by names such as ethyl alcohol, alcohol, absolute, or 1-hydroxyethane, is a clear, volatile liquid characterized by its molecular formula C2H6O and a molecular weight of approximately 46.07 g/mol. Its sensory profile includes a medium-strength alcoholic odor with floral and fruity notes reminiscent of ripe apples. This alcohol is widely found naturally in diverse plants including fruits, vegetables, and herbs. It serves as a fundamental compound in organic chemistry and is available commercially in various purity grades, including USP and absolute forms. The linked controlled vocabulary for ethanol is available at PubChem. Ethanol is typically produced via fermentation processes or industrial synthesis for use in numerous applications.

Occurrence, Applicability & Potential Uses

Ethanol occurs naturally in various plant sources such as apples, citrus fruits including lemon, lime, mandarin, and orange, as well as vegetables like broccoli, carrot, and tomato. It is present in fruits like fig, guava, peach, pineapple, plum, and raspberry, among others. The compound functions primarily as a carrier solvent and diluent in flavor and fragrance formulations due to its solvency and volatility. Additionally, it is employed as an extraction solvent in diverse applications. The regulation of ethanol in flavorings and food products is governed by standards such as FEMA (Flavor and Extract Manufacturers Association) in the United States, which evaluates its usage levels and safety profiles.

Physico-Chemical Properties Summary

Ethanol is a low molecular weight alcohol with notable volatility, boiling at 78 to 79°C under standard atmospheric pressure. It exhibits a specific gravity around 0.77 at 25°C and a refractive index between 1.31 and 1.36. The vapor pressure at 20°C is measured at approximately 44.6 mm Hg, contributing to its rapid evaporation in formulations. Its solubility in water is high, facilitating its role as a universal solvent. The compound has a flash point around 49°F (9°C), indicating significant flammability. Its log P value of about -0.19 reflects moderate hydrophilicity, relevant for its partitioning behavior in mixtures. These physicochemical properties influence its function as an effective solvent and carrier in diverse product formulations.

FAQ

What is ethanol and how is it commonly identified?
Ethanol is a basic alcohol with the molecular formula C2H6O, characterized as a clear, volatile liquid with a medium-strength alcoholic odor. It is commonly known as ethyl alcohol and referred to by synonyms such as absolute alcohol, grain alcohol, or 1-hydroxyethane. It is widely used as a solvent and flavor carrier and is naturally present in various plants and fruits. Ethanol is identified by identifiers like CAS number 64-17-5 and FEMA number 2419.
Where does ethanol occur naturally and what are its main uses?
Ethanol is naturally found in a broad variety of plants including fruits like apples, citrus species, fig, guava, and peach, as well as vegetables such as broccoli, carrot, and tomato. Its main application is as a carrier solvent and diluent in flavor and fragrance formulations, owing to its excellent solvency and volatility. It is also used as an extraction solvent. These roles make ethanol a critical component in food flavoring and industrial products.
How is ethanol regulated and what safety considerations apply?
Ethanol's use in flavorings and food products is regulated by organizations like FEMA in the United States, which sets generally recognized as safe (GRAS) usage levels for various food categories. Safety information notes its highly flammable nature and potential irritancy to eyes, respiratory system, and skin, requiring appropriate handling precautions. International standards including REACH (EU) also govern ethanol's registration and safe use. Users are advised to observe hazard statements and follow safe storage and handling practices.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

ethanol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:64-17-5
Pubchem (cid):702
Pubchem (sid):134971966
Flavornet:64-17-5
Pherobase:View
Publications by Info
Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.)

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C00469
HMDB (The Human Metabolome Database):HMDB00108
FooDB:FDB000753
YMDB (Yeast Metabolome Database):YMDB00883
Export Tariff Code:2905.19.0060
FDA Listing of Food Additive Status:View
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•grades: usp (95% by vol); absolute; pure; completely denatured; specially denatured; industrial, various proofs . •materials containing alcohol: apple distillate k 2032410; arnica distillate 2378370; birch distillate 2384280; chamomille distillate 2380930; linden blossom distillate 2382920 •to every 100 gal of ethyl alcohol add: four gal of methyl alcohol and one gal of methyl isobutyl ketone; or four gal methyl alcohol and 18 avoirdupois oz denatonium benzoate, nf •to every 100 gal of ethyl alcohol add: one-half gal benzene or one-half gal rubber hydrocarbon solvent. •to every 100 gal of ethyl alcohol add: thirty-three pounds, or more, metallic sodium and either one-half gal benzene or one-half gal rubber hydrocarbon solvent •to every 100 gal of ethyl alcohol add: five gal methyl alcohol •to every 100 gal of ethyl alcohol add: one gal of pine tar nf •to every 100 gal of ethyl alcohol add: one gal of the following solution: five gal of an aq soln containing 40% nicotine; and 3.6 avoirdupois oz of methylene blue, nf; water sufficient to make 100 gal •to every 100 gal of ethyl alcohol add: five gal of benzene •to every 100 gal of ethyl alcohol add: ten gal of ethyl ether •to every 100 gal of ethyl alcohol add: five-hundredths gal of bone oil (dipple's oil) •to every 100 gal of ethyl alcohol add: one hundred gal of ethyl ether •to every 100 gal of ethyl alcohol add: ten gal of formaldehyde soln (usp) •to every 100 gal of ethyl alcohol add: ten gal of acetone, nf •to every 100 gal of ethyl alcohol add: three pounds of salicyclic acid, usp, one pound resorcin, usp, and 1 gal bergamont oil, nf, or bay oil, nf •to every 100 gal of ethyl alcohol add: eight gal of acetone, nf and 1.5 gal of methyl isobutyl ketone •to every 100 gal of ethyl alcohol add: twenty pounds of iodine, usp and 15 pounds of either potassium or sodium iodide usp •to every 100 gal of ethyl alcohol add: a soln composed of 20 pounds of iodine usp, 15 pounds of potassium or sodium iodide usp and 15 pounds of water. •to every 100 gal of ethyl alcohol add: one gal of rosemary oil, nf and 30 lb of camphor, usp •to every 100 gal of ethyl alcohol add: thirty-five lb of camphor, usp and 1 gal of clove oil, usp •to every 100 gal of ethyl alcohol add: one gal of lavender oil, usp and 100 lb of medicinal soft soap, usp •to every 100 gal of ethyl alcohol add: ten gal of methyl alcohol •to every 100 gal of ethyl alcohol add: one hundred lb of glycerol, usp and 20 lb of hard soap, nf •to every 100 gal of ethyl alcohol add: thirty lb of methyl violet, usp •to every 100 gal of ethyl alcohol add: 29.75 gal of ethyl acetate having an ester content of 100% by wt or the equivalent thereof not to exceed 35 gal of ethyl acetate with an ester content of not less than 85% by wt •to every 100 gal of ethyl alcohol add: 4.25 gal of ethyl acetate having an ester content of 100% by wt or the equivalent thereof not to exceed 5 gal of ethyl acetate with an ester content of not less than 85% by wt •to every 100 gal of ethyl alcohol add: 3 gal of ammonia, aq, 27 to 30% by wt: three gal of strong ammonia soln, usp: 17.5 lb of caustic soda, liq grade, containing 50% sodium hydroxide by wt: or 12.0 lb of caustic soda, liq grade, containing 73% sodium hydroxide by wt. •to every 100 gal of ethyl alcohol add: 45 fluid oz of eucalyptol, usp, 30 avoirdupois oz of thymol, nf and 20 avoirdupois oz of mentol, usp •to every 100 gal of ethyl alcohol add: ten lb of any one or a total of 10 lb of two or more of the oils and substances listed below: anethole, usp; anise oil, usp; bay oil (myrcia oil), nf; benzaldehyde, nf; bergamot oil, nf; bitter almond oil, nf; camphor, usp; cedar leaf oil, usp, xiii; chlorothymol, nf; cinnamic aldehyde, nf, ix; cinnamon oil (cassia oil), usp; citronella oil, natural; clove oil, usp; coal tar, usp; eucalyptol, usp; eucalyptus oil, nf; eugenol, usp; guaiacol, nf; lavender oil, usp; menthol, usp; mustard oil, volatile (allyl isothiocyanate), usp, xii; peppermint oil, usp; phenol, usp; phenyl salicylate (salol), nf; pine oil, nf; pine needle oil, dwarf, nf; rosemary oil, nf; safrol; sassafras oil, nf; spearmint oil, nf; spearmint oil, terpeneless; spike lavender oil, natural; storax, usp; thyme oil, nf; thymol, nf; tolu balsam, usp; turpentine oil, nf; wintergreen oil (methyl salicylate), usp •to every 100 gal of ethyl alcohol add: 10 lb of menthol, usp and 1.25 gal of formaldehyde soln, usp •to every 100 gal of ethyl alcohol add: two and one-half lb of menthol, usp and 2.5 gal of formaldehyde soln, usp •to every 100 gal of ethyl alcohol add: (1) six lb of boric acid, usp, 1 and 13 lb thymol, nf, 1 and 13 lb chlorothymol, nf and 1 and 13 lb menthol, usp; or (2) seven lb of boric acid, usp, and a total of 3 lb of any two or more denaturing materials listed under sda no 38-b •to every 100 gal of ethyl alcohol add: nine lb of sodium salicylate or salicylic acid, usp, 1.25 gal fluid extract of quassia, nf, vii and 18 gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: sixty avoirdupois oz of any one of the following alkaloids or salts together with 18 gal of tertiary butyl alcohol: quinine, nf; quinine bisulfate, nf; quinine hydrochloride, usp; cinchonidine; cinchonidine sulfate, nf, ix •to every 100 gal of ethyl alcohol add: two and 12 gal of diethylphthalate and 18 gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: one gal of diethylphthalate •to every 100 gal of ethyl alcohol add: one gal of bay oil, nf and either 50 avoirdupois oz of quinine sulfate, usp, 50 avoirdupois oz of quinine bisulfate, nf, or 200 avoirdupois oz of sodium salicylate, usp •to every 100 gal of ethyl alcohol add: one and one-half avoirdupois oz of brucine (alkaloid), or brucine sulfate (nf, ix), or quassin, or one and one-half av oz of any combination of two or of three of those denaturants, and 18 gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: one lb of sucrose octa-acetate and 18 gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: one-sixteenth avoirdupois oz of denatonium benzoate, nf, (bitrex) and 18 gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: three gal of tertiary butyl alcohol •to every 100 gal of ethyl alcohol add: eighty g of potassium iodide, usp and 109 g of red mercuric iodide, nf or 95 g of thimerosal, nf or 76 g of any of the following: phenyl mercuric nitrate, nf; phenyl mercuric chloride, nf; or phenyl mercuric benzoate •to every 100 gal of ethyl alcohol add: ten gal of n-butyl alcohol •to every 100 gal of ethyl alcohol add: three hundred lb of refined white or orange shellac •to every 100 gal of ethyl alcohol add: 25 fluid oz of phenol, usp and 4 fluid oz of wintergreen oil (methyl salicylate), usp •grades of purity: anhydrous (200 proof); 190 proof •preparations: alcohol & dextrose injectio, usp; ethanol for disinfection; evaporating lotion; high alcoholic elixir; iso-alcoholic elixir; low alcoholic elixir; spirit ear-drops

General Material Information

Preferred name ethanol
Trivial Name Ethanol
Short Description ethyl alcohol
Formula C2 H6 O
CAS Number 64-17-5
FEMA Number 2419
Flavis Number 2.078
ECHA Number 200-578-6
FDA UNII 3K9958V90M
Beilstein Number 1718733
MDL MFCD00003568
COE Number 11891
xLogP3-AA -0.10 (est)
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 41 ethanol
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 64-17-5 ; ETHYL ALCOHOL
Synonyms
  • 1-hydroxyethane
  • aethylalkohol
  • alcohol, absolute
  • alcohol, ethyl
  • alcohol, grain
  • alcool ethylique
  • alcool etilico
  • ethicap
  • ethyl alcohol
  • ethyl alcohol - pure
  • ethyl alcohol natural 200 proof USP
  • ethyl hydroxide
  • ethylol
  • etylowy alkohol
  • GNS beverage alcohol
  • hinetoless
  • hydroxyethane
  • infinity pure
  • methyl carbinol
  • N- ethanol
  • punctilious
  • silent spirit
  • tecsol A solvent, anhydrous
  • tecsol D-2 solvent, anhydrous
  • thanol
  • Alcohol
  • Algrain
  • Anhydrol
  • Ethyl hydrate
  • Jaysol
  • Jaysol S
  • Methylcarbinol
  • Molasses alcohol
  • Potato alcohol
  • Tecsol
  • Alcohol anhydrous
  • Denatured ethanol
  • Tecsol C
  • Alcare Hand Degermer
  • SY Fresh M
  • Synasol
  • Desinfektol EL
  • Duplicating Fluid 100C.NPA
  • 100C.NPA
  • Anhydrol PM 4085
  • SDA 3A
  • Esumiru WK 88
  • IMS 99
  • Lux
  • AHD 2000
  • Sekundasprit
  • NSC 85228
  • CDA 19
  • CDA 19-200
  • Sterillium Rub
  • Germ-X
  • Vinic alcohol
  • SD 3A
  • Denatured alcohol
  • Neocol CQ
  • Black Warrant
  • Bioethanol
  • Surfin 96
  • SDA 23A
  • Amanol SD
  • Alpet E
  • Alpet NV
  • PM 6193-200
  • ICON Dry
  • Adechiru 750
  • Traceable 95
  • Shunkol B
  • Prethanol A
  • LEK 01
  • 95PGF2
  • ProtectorPlus gel
  • THS gel
  • SD 29 (alcohol)
  • MeSH ID: D000431
  • Drysol NM
  • Traceable 99

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 46.069019317627
Specific gravity 0.772 - 0.786 @ 25 °C
Pounds per Gallon 6.424 to 6.54
Refractive Index 1.31 to 1.36 @ 20 °C
Melting Point -115 to -114°C @ 760 mm HG
Boiling Point 78 to 79°C @ 760 mm HG
Boiling Point 22 to 23°C @ 50 mm HG
Vapor Pressure 44.6 mm HG @ 20 °C
Vapor Density 1.59
Flash Point TCC Value 9.44 °C TCC
logP (o/w) -0.19
Solubility
water, 7.921e+005 mg/L @ 25 °C (est) Yes
water, 1.00E+06 mg/L @ 25 °C (exp) Yes

Organoleptic Properties

Odor Type: Alcoholic
alcoholic, ethereal, medicinal
Odor strength medium
Substantivity < 1 hour(s) at 100.00 %
General comment At 100.00 %. strong alcoholic ethereal medical
VCF-online.nl Alcohol, floral, ripe apple, sweet

Occurrences

Safety Information

Safety information

European information :
Most important hazard(s):
F - Highly flammable.
R 11 - Highly flammable.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 7060 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 16, Pg. 718, 1970.

intravenous-rat LD50 1440 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971.

intraperitoneal-rat LD50 3600 mg/kg
Pharmacology: International Journal of Experimental and Clinical Pharmacology. Vol. 2, Pg. 27, 1969.

oral-rabbit LD50 6300 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.

intravenous-rabbit LD50 2374 mg/kg
EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.

intraperitoneal-rabbit LD50 963 mg/kg
EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.

oral-mouse LD50 3450 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(3), Pg. 31, 1967.

intravenous-mouse LD50 1973 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955.

intraperitoneal-mouse LD50 528 mg/kg
Strahlentherapie. Vol. 127, Pg. 245, 1965.

intravenous-cat LDLo 3945 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.

oral-cat LDLo 6000 mg/kg
GASTROINTESTINAL: GASTRITIS KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"
Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936.

intravenous-chicken LDLo 8216 mg/kg
VASCULAR: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 312, 1937.

oral-child LDLo 2000 mg/kg
LIVER: FATTY LIVER DEGERATION BLOOD: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Toxikologie. Vol. 17, Pg. 183, 1958.

oral-child TDLo 14400 mg/kg/30
LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING
Acta Paediatrica Scandinavica. Vol. 74, Pg. 977, 1985.

intraperitoneal-dog LDLo 3000 mg/kg
British Journal of Industrial Medicine. Vol. 1, Pg. 207, 1944.

intravenous-dog LDLo 1600 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971.

oral-dog LDLo 5500 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.

parenteral-frog LDLo 36000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.

intraperitoneal-guinea pig LD50 3414 mg/kg
EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.

oral-guinea pig LD50 5560 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

intraperitoneal-hamster LD50 5068 mg/kg
EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.

oral-human LDLo 1400 mg/kg
BEHAVIORAL: SLEEP BEHAVIORAL: HEADACHE GASTROINTESTINAL: NAUSEA OR VOMITING
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974.

intraperitoneal-mammal (species unspecified) LD50 4300 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Toxicology and Applied Pharmacology. Vol. 13, Pg. 358, 1968.

oral-man TDLo 1430 ug/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC BEHAVIORAL: ATAXIA
Journal of Pharmacology and Experimental Therapeutics. Vol. 197, Pg. 488, 1976.

oral-man TDLo 3371 uL/kg
BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Veterinary and Human Toxicology. Vol. 21, Pg. 272, 1979.

oral-man TDLo 50 mg/kg
GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION GASTROINTESTINAL: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936.

oral-man TDLo 700 mg/kg
BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS
Neurobehavioral Toxicology and Teratology. Vol. 8, Pg. 77, 1986.

oral-man TDLo 22500 mg/kg/4W
ENDOCRINE: OTHER CHANGES BLOOD: OTHER CHANGES
Clinical Endocrinology Vol. 25, Pg. 143, 1986.

Dermal Toxicity:
skin-rabbit LDLo 20000 mg/kg
"Alcohols: Their Chemistry, Properties and Manufacture," Monick, J.A., New York, Reinhold Book, 1968Vol. -, Pg. 72, 1968.

subcutaneous-mouse LD50 8285 mg/kg
FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970.

subcutaneous-chicken LDLo 5000 mg/kg
"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.

subcutaneous-dog LDLo 6000 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.

subcutaneous-frog LDLo 7100 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955.

subcutaneous-rabbit LDLo 20000 mg/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 651, 1980.

Inhalation Toxicity:
inhalation-rat LC50 20000 ppm/10H
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974.

inhalation-mouse LC50 39000 mg/m3/4H
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(8), Pg. 53, 1982.

inhalation-guinea pig LCLo 21900 ppm
FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970.

Safety in use information

Category:
carrier solvents/deluents for flavor and/or fragrance agents; extraction solvent
Recommendation for ethanol usage levels up to:
not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -1800.00000
beverages(nonalcoholic): -1700.00000
beverages(alcoholic): 250.00000450000.00000
breakfast cereal: --
cheese: --
chewing gum: -1400.00000
condiments / relishes: -1000.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -2000.00000
fruit ices: -2000.00000
gelatins / puddings: -230.00000
granulated sugar: --
gravies: --
hard candy: -2200.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: -30.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 11, Revision 1 (FGE.11Rev1) - Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 14, Revision 1 (FGE.14Rev1): Phenethyl alcohol, aldehyde, acetals, carboxylic acid and related esters from chemical group 15 and 22 [1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf

Flavouring Group Evaluation 61, Revision 1 (FGE.61Rev1): Consideration of aliphatic acetals evaluated by JECFA (57th meeting) structurally related to acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated aldehydes and one orthoester of formic acid evaluated
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf

Flavouring Group Evaluation 5, Revision 2 (FGE.05Rev2): Branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols from chemical groups 1, 2, 3 and 5
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf

Scientific Opinion on the evaluation of the substances currently on the list in the Annex to Commission Directive 96/3/EC as acceptable previous cargoes for edible fats and oils – Part I of III
View page or View pdf

Scientific Opinion on the safety and efficacy of straight-chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species
View page or View pdf

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):64-17-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :702
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1170
WGK Germany:1
ethanol
Chemidplus:0000064175
EPA/NOAA CAMEO:hazardous materials
RTECS:64-17-5