2-(thienyl-2)-ethanethiol acetate

2-(thienyl-2)-ethanethiol acetate is an organosulfur compound known for burnt and onion-like flavor notes, used solely for informational study without applications in fragrances or flavors.

General Material Description

2-(thienyl-2)-ethanethiol acetate is an organosulfur compound characterized by the presence of a thiol acetate functional group attached to a thienyl-ethyl moiety. This compound typically appears as a clear liquid or low-melting solid with sensory properties reminiscent of burnt and onion-like aromas. It belongs to a class of thiol esters that are structurally related to sulfur-containing heterocycles, which often contribute to distinctive organoleptic characteristics. Synonyms for this material include 2-(2-thienyl)-ethanethiol acetate, 2-(2-thienyl)ethanethiol acetate, and 2-(2-thienyl) ethane thiol acetate. It is cataloged under controlled vocabulary databases such as PubChem. The compound is primarily of academic interest and is obtained synthetically via acetylation of the corresponding thiol derivative.

Occurrence, Applicability & Potential Uses

Although 2-(thienyl-2)-ethanethiol acetate does not occur naturally in biological systems, its structural components resemble fragments found in various sulfur-containing biomolecules and natural products. Because of its distinctive burnt and onion flavor notes, it might conceptually relate to compounds contributing to aroma profiles in certain foods or industrial processes; however, this compound is explicitly not used in fragrance or flavor formulations. Safety and usage guidelines align with the REACH (EU) regulation framework, emphasizing that this molecule is intended solely for informational or research purposes rather than commercial utilization in food or perfumes.

Physico-Chemical Properties Summary

The presence of a thienyl ring fused with an ethanethiol acetate group defines the compound's chemical reactivity, particularly in sulfur chemistry contexts. Its functional groups contribute to moderate volatility with a pronounced odor profile. The acetate ester functions as a protecting group for the thiol, influencing its stability and reactivity under standard conditions. The lipophilicity imparted by the aromatic thienyl ring may affect solubility behavior in organic solvents, while the overall molecular geometry suggests limited polarity. These properties collectively restrict its application scope, especially in formulations requiring fragrance or flavor attributes, steering use toward chemical research instead.

FAQ

What is 2-(thienyl-2)-ethanethiol acetate and what are its key characteristics?

2-(thienyl-2)-ethanethiol acetate is an organosulfur compound featuring a thienyl ring bonded to an ethanethiol acetate group. It exhibits distinctive burnt and onion-like flavor notes, although it is not applied in flavor or fragrance products. It exists mainly as a synthetic chemical used for study rather than commercial exploitation. This compound is also known by synonyms such as 2-(2-thienyl)-ethanethiol acetate and 2-(2-thienyl)ethanethiol acetate.

How is 2-(thienyl-2)-ethanethiol acetate typically sourced and what are its usage limitations?

This compound is synthesized through chemical methods involving acetylation of thiol precursors rather than being isolated from natural sources. It is not approved or recommended for use in fragrances or flavorings, restricting its application to informational and research contexts. Safety and regulatory documents specify that typical exposure or formulation does not include this compound, with usage limited by guidelines such as those outlined in REACH (EU). No established exposure limits or toxicological data are available for general use.

What regulatory considerations and safety information exist for 2-(thienyl-2)-ethanethiol acetate?

Current classification under the GHS (Globally Harmonized System) via OSHA HCS (US) identifies no specific hazards or pictograms for 2-(thienyl-2)-ethanethiol acetate. There are no formal hazard or precautionary statements assigned. Toxicological endpoints including oral, dermal, and inhalation toxicity have not been determined. Regulatory frameworks such as REACH (EU) categorize the compound as not intended for consumer use in flavors or fragrances. Safety information is primarily informational, with no regulatory registration for commercial flavor or fragrance applications.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar	Start search
Google Books	Start search
Google Patents	Start search
Perfumer & Flavorists	Start search
EU Patents	Start search
PubMeb	Start search
NCBI	Start search

Literature & References

None found

Publications by US Patents
3,952,024 - Furfurylthioacetone
Certain 2,5-dimethyl-3-thiopyrazines
Flavoring agent

Other Information

General Material Information

Trivial Name	2-(thienyl-2)-ethanethiol acetate
Synonyms	2-(2-thienyl)-ethanethiol acetate 2-(2-thienyl)ethanethiol acetate 2-(2-thienyl) ethane thiol acetate

PhysChem Properties

Material listed in food chemical codex

Organoleptic Properties

Flavor Type: Burnt
burnt, onion
General comment	Burnt, onion

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for 2-(thienyl-2)-ethanethiol acetate usage levels up to:
	not for fragrance use.

Recommendation for 2-(thienyl-2)-ethanethiol acetate flavor usage levels up to:
	not for flavor use.

Safety references

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search